金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:Q61527 N-terminal Sequence Analysis:No results obtained: Gln26 predicted Purity:>85%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:97.5 kDa (monomer) SDS-PAGE:120-140 kDa, reducing conditions Activity:Measured by its ability to inhibit the biological activity of Neuregulin-1-beta 1 on MCF‑7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083.The ED₅₀ for this effect is typically 3 - 12 µg/mL in the presence of 10 ng/mL of rhNRG-1 beta 1 (R&D Systems, Catalog # 377-HB). Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: ErbB4/Her4 Long Name: Receptor Tyrosine Protein Kinase ErbB4 Aliases: HER4 Entrez Gene IDs: 2066 (Human); 13869 (Mouse); 59323 (Rat) Background: ErbB4 ErbB4, also known as Her4, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the EGF family of growth factors. ErbB4 ligands include the neuregulins, betacellulin and heparin-binding EGF-like growth factor (HB-EGF).