货号：07-306

品牌：Merck Millipore

规格：

目录价：￥3639.00

市场价格：￥3093.15

会员价格：￥2911.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CtBP-1 Antibody | 07-306 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: CtBP-1 View All» Molecular Weight: 53kDa View All» Immunogen: peptide corresponding to amino acids 425-440 (QTVKPEADRDHASDQL) of human CtBP-1 View All» Isotype: IgG View All» Background Information: The phosphoprotein C-terminal binding protein 1 (CtBP1) binds the C-terminus of adenovirus E1A protein. CtBP1 is a transcriptional repressor and may play a role during cellular proliferation. View All» Species Reactivity:

• Human

• Mouse
  View All» Control: HeLa nuclear extract View All» Quality Assurance: routinely evaluated by immunoblot on nuclear extract from HeLa cells, as well as in RIPA lysates from 3T3/A31, A431 or Jurkat cells View All» Purification Method: Protein A chromatography View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: Q13363 View All» Entrez Gene Number: NM_001328 View All» Gene Symbol:
  • CTBP1

  • CtBP1

  • BARS

  • MGC104684

  • CTBP
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. View All» UniProt Summary: FUNCTION: SwissProt: Q13363 # Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity). Co- repressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.COFACTOR: NAD. Required for efficient interaction with E1A. Cofactor binding induces a conformation change.SIZE: 440 amino acids; 47535 Da SUBUNIT: Interacts with the C-terminus of adenovirus E1A protein, ELK3 and CTIP via their consensus motif P-X-[DNS]-L-[STVA]. Can form homodimers or heterodimers of CTBP1 and CTBP2. Interacts with FOXP2, HDAC4, HDAC5 and HDAC9. Interacts with GLIS2 but not GLIS1 or GLIS3 (By similarity). Interacts with FOXP1, HIPK2, PNN and NRIP1. Interacts with ZFHX1B and WIZ.SUBCELLULAR LOCATION: Cytoplasm. Nucleus.PTM: The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage, probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation. & ADP-ribosylated; when cells are exposed to brefeldin-A (BFA) (By similarity). & Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.SIMILARITY: SwissProt: Q13363 ## Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. View All» Brand Family: Upstate View All» Product Name: Anti-CtBP-1 Antibody | 07-306 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Rabbit View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://16ao.com/thread-135399.htm
      © Merck Millipore代理07-306 Anti-CtBP-1 (Rabbit Polyclonal IgG)，产品报价联系微信jinshanbio