货号：07-250

品牌：Merck Millipore

规格：100Ug

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PP2A Antibody, A subunit | 07-250 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: PP2A A subunit, α isoform View All» Molecular Weight: 63-65kDa View All» Immunogen: KLH-conjugated, synthetic peptide of 13 amino acids (MAAADGDDSLY-Ahx-C), containing amino acids 1-11 of human PP2A, A subunit. Ahx is aminohexanoic acid. The immunizing sequence is conserved in human, mouse, rat, porcine and Xenopus. View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse

• Pig

• Rat

• Xenopus
  View All» Quality Assurance: Routinely evaluated by immunoblot on RIPA lysates from 3T3/A31 cells. View All» Purification Method: Immunoaffinity chromatography View All» Presentation: 100mM triethylamine, 100mM sodium phosphate, 0.02% sodium azide before the addition of glycerol to 30%. View All» Storage Conditions: 1 year at -20°C View All» UniProt Number: P30154 View All» Entrez Gene Number: NM_002716 View All» Gene Symbol:
  • PPP2R1B

  • MGC26454

  • PP2A-A-beta

  • PR65B
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Defects in this gene could be the cause of some lung and colon cancers. At least two transcript variants encoding different isoforms have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P30154 # The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.SIZE: 601 amino acids; 66214 Da SUBUNIT: PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with IPO9.DOMAIN: SwissProt: P30154 Each HEAT repeat appears to consist of two alpha helices joined by a hydrophilic region, the intrarepeat loop. The repeat units may be arranged laterally to form a rod-like structure.DISEASE:SwissProt: P30154 # Defects in PPP2R1B might be a cause of some lung and colorectal cancers.SIMILARITY: Belongs to the phosphatase 2A regulatory subunit A family. & Contains 15 HEAT repeats. View All» Brand Family: Upstate View All» Product Name: Anti-PP2A Antibody, A subunit | 07-250 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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