R&D Systems代理4055-CR-050 Recombinant Human Cyr61/CCN1 Fc Chimera Protein, CF (50 UG)-试剂-金山科研平台

R&D Systems代理4055-CR-050 Recombinant Human Cyr61/CCN1 Fc Chimera Protein, CF (50 UG)

2025-06-28

货号：4055-CR-050

品牌：R&D Systems

规格：50ug

目录价：￥4350.00

市场价格：￥3480.00

会员价格：￥3480.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived Accession #:O00622 N-terminal Sequence Analysis:Ala22 Structure:Disulfide-linked homodimer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:66.3 kDa SDS-PAGE:70-75 kDa, reducing conditions Activity:Measured by its ability to mediate Balb/3T3 mouse embryonic fibroblast cell adhesion. Ball, D.K. etal. (2003) Reproduction 125:271. Recombinant Human Cyr61/CCN1 Fc Chimera immobilized at 1.5 µg/mL, 100µL/well, will mediate > 25% BALB/3T3 cell adhesion (3 x 10⁴ cell/well added). Formulation:Lyophilized from a 0.2 µm filtered solution in PBS and NaCl.See Certificate of Analysis for details. Molecule Information: Cyr61/CCN1 Long Name: Cysteine-Rich, Angiogenic Inducer 61 Aliases: CCN1; GIG1; IGFBP-10 Entrez Gene IDs: 3491 (Human); 16007 (Mouse); 83476 (Rat) Background: Cyr61

View Cyr61 IHC images. Cyr61, also known as IGFBP-10 and CCN1, is a 50 kDa matricellular glycoprotein that regulates the growth and adhesion of vascular endothelial cells, fibroblasts, and monocytes. Cyr61 induces VEGF upregulation, angiogenesis, and tumorigenesis through interactions with integrins alpha V beta 3, alpha V beta 5, alpha M beta 2, and alpha 6 beta 1. Cyr61 is cleaved by plasmin within its VWF domain which generates an N-terminal fragment that is not associated with the matrix but retains the ability to induce endothelial cell migration.

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