货号：07-1825

品牌：Merck Millipore

规格：

目录价：￥3908.00

市场价格：￥3321.80

会员价格：￥3126.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-FRS3/FRS2β Antibody | 07-1825 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes FRS3/ FRS2β. View All» Molecular Weight: 54 kDa View All» Epitope: PTB View All» Immunogen: KLH-conjugated linear peptide corresponding to amino acids 361-375 of FRS3/ FRS2β. View All» Background Information: Fibroblast growth factor receptor substrate 3 (FRS3) is an adapter protein that is tyrosine phosphorylated and recruited to FGFR upon FGF stimulation. FRS3 is also designated as FRS2 and SNT2 (Suc1 associated neurotrophic factor target protein). View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Proven to react with human, mouse, and rat. View All» Control: Mouse brain tissue lysate View All» Quality Assurance: Evaluated by Western Blot in mouse brain tissue lysate.Western Blot Analysis: A 1:2,000 dilution of this antibody detected FRS3/ FRS2β in mouse brain tissue lysate. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit serum in PBS containing 0.05% sodium azide. View All» Storage Conditions: Maintain refrigerated at 2-8°C for 1 year from date of receipt. View All» UniProt Number: O43559 View All» Entrez Gene Number: NP_659188 View All» Gene Symbol:
  • FRS2-beta

  • FRS2B

  • FRS2beta

  • MGC17167

  • OTTHUMP00000016383

  • OTTHUMP00000039786

  • SNT-2

  • SNT2
    View All» Alternate Names:
    • FGFR substrate 3

    • FGFR-signaling adaptor SNT2

    • Suc1-associated neurotrophic factor target 2

    • fibroblast growth factor receptor substrate 3

    • suc1-associated neurotrophic factor target 2 (FGFRsignalling adaptor)
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. SUBUNIT STRUCTURE: Binds NTRK1 By similarity. Binds FGFR1, NGFR, GRB2, PTPN11 and ERK2.SUBCELLULAR LOCATION: Membrane; Lipid-anchor. PTM: Phosphorylated on tyrosine residues upon stimulation by BFGF or NGFB. SEQUENCE SIMILARITIES: Contains 1 IRS-type PTB domain. View All» Product Name: Anti-FRS3/FRS2β View All» Concentration: 0.47 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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