金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived Accession #:P97677 N-terminal Sequence Analysis:Ser22 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:82.6kDa (monomer) SDS-PAGE:90-95 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.When rrNotch-1 (Catalog # 1057-TK) is coated at 5 µg/mL, rrDLL-1 binds with an apparent K_D < 5 nM. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: DLL1 Long Name: Delta-like 1 Aliases: Delta 1 Entrez Gene IDs: 28514 (Human); 13388 (Mouse); 84010 (Rat) Background: DLL1

DLL1 localizes to adherens junctions on neuronal processes through its association with the scaffolding protein MAGI1. DLL1 is widely expressed, and it plays an important role in embryonic somite formation, cochlear hair cell differentiation, plus B and T lymphocyte differentiation. The upregulation of DLL1 in arterial endothelial cells following injury or angiogenic stimulation is central to postnatal arteriogenesis. DLL1 is also overexpressed in cervical carcinoma and glioma and contributes to tumor progression.