R&D Systems代理389-LR-100 Recombinant Human Leptin R Fc Chimera Protein (100 UG)-试剂-金山科研平台

R&D Systems代理389-LR-100 Recombinant Human Leptin R Fc Chimera Protein (100 UG)

2025-06-25

货号：389-LR-100

品牌：R&D Systems

规格：100ug

目录价：￥4760.00

市场价格：￥3808.00

会员价格：￥3808.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:P48357 N-terminal Sequence Analysis:Thr20 Structure:Disulfide-linked homodimer Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:121 kDa (monomer) SDS-PAGE:155-175kDa, reducing conditions Activity:Measured by its ability to inhibit Leptin-dependent proliferation of BaF3 mouse pro‑B cells transfected with human Leptin R.The ED₅₀ for this effect is typically 0.02-0.12 µg/mL in the presence of 3 ng/mL recombinant human Leptin. Molecule Information: Leptin R Long Name: Leptin Receptor Aliases: B219; CD295; LEPR; OB R Entrez Gene IDs: 3953 (Human); 16847 (Mouse) Background: Leptin Receptor

View Leptin R IHC images. Leptin receptor (OBR), also named B219, is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130, G-CSF receptor, and the LIF receptor. Multiple isoforms of human and mouse OBR, including a long form (OBRL) with a large cytoplasmic domain capable of signal-transduction, and several receptor isoforms with short cytoplasmic domains (OBRS) lacking signal-transducing capabilities, have been identified.

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