金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:P37023 N-terminal Sequence Analysis:Asp22 Structure:Disulfide-linked homodimer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:37.3 kDa (monomer) SDS-PAGE:50-55 kDa, reducing conditions Activity:Measured by its ability to inhibit BMP-9-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953.The ED₅₀ for this effect is typically 3 - 12 ng/mL in the presence of 2 ng/mL of rhBMP-9. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: ALK-1 Long Name: Activin Receptor-like Kinase 1 Aliases: ACVRL1 Entrez Gene IDs: 94 (Human); 11482 (Mouse) Background: ALKs (Activin Receptor-like Kinases) ALKs 1-7 are type I serine/threonine kinase receptors for TGF-beta superfamily members. They undergo hetero-oligomerization with type II serine/threonine kinase receptors to transduce signals, usually through Smad proteins. Alk-1 binds TGF-beta and Alk-7 is thought to bind nodal.