金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Ser23-Leu350, with a C-terminal 6-His tag Accession #:Q9CYA0 N-terminal Sequence Analysis:Ser23 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:36.8 kDa SDS-PAGE:57-62 kDa, reducing conditions Activity:Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells.The ED₅₀ for this effect is typically0.75-3 µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: CRELD2 Long Name: Cysteine-rich Protein With EGF-like Domains 2 Entrez Gene IDs: 79174 (Human); 76737 (Mouse) Background: CRELD Family The CRELDs are integral membrane proteins that function as cell adhesion molecules. They are alternatively spliced and are ubiquitously expressed during development and in mature tissues. Missense mutations in CRELD1 increase susceptibility to atrioventricular septal defects (AVSD), while CRELD2 has been shown to interact with the alpha 4 subunit of the nicotinic acetylcholine receptor and function as a specific regulator of receptor expression.