货号：07-1396

品牌：Merck Millipore

规格：EA

目录价：￥3024.00

市场价格：￥2570.40

会员价格：￥2419.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PP-1B Antibody | 07-1396 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes PP-1B. View All» Molecular Weight: 37 kDa View All» Epitope: N/A View All» Immunogen: KLH-conjugated linear peptide corresponding to human PP-1B. View All» Background Information: Type 1 protein Ser/Thr phosphatases (PP1) have a high specific activity against phosphorylase, and are resistant to okadaic acid up to concentrations of 50 nM, but sensitive to Inhibitor-2 and microcystin LR. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Reacts with human, mouse, and rat. View All» Control: Hek293 cell lysate View All» Quality Assurance: Evaluated by Western Blot in Hek293 cell lysate.Western Blot Analysis: A 1:1,000 dilution of this antibody detected PP-1B on 10 µg of Hek293 cell lysate. View All» Purification Method: Unpurified View All» Presentation: Unpurified rabbit serum with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P62140 View All» Entrez Gene Number: NP_002700.1 View All» Gene Symbol:
  • PPP1CB

  • PP-1B

  • PPP1CD
    View All» Alternate Names:
    • protein phosphatase 1, catalytic subunit, beta

    • protein phosphatase 1, catalytic subunit, beta isoform

    • protein phosphatase 1, catalytic subunit, delta isoform

    • protein phosphatase 1-beta

    • protein phosphatase 1-delta

    • serine/threonine protein phosphatase PP1-beta catalytic subunit
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq] View All» UniProt Summary: FUNCTION: Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity.COFACTOR: Binds 1 iron ion per subunit (By similarity). & Binds 1 manganese ion per subunit (By similarity).SIZE: 327 amino acids; 37187 Da SUBUNIT: PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC, which is folded into its native form by inhibitor 2 and glycogen synthetase kinase 3, and then complexed to one or several targeting or regulatory subunits. PPP1R12A and PPP1R12B mediate binding to myosin. PPP1R3A, PPP1R3B, PPP1R3C and PPP1R3D mediate binding to glycogen (By similarity). Interacts with PPP1R7.SUBCELLULAR LOCATION: Cytoplasm (By similarity).SIMILARITY: Belongs to the PPP phosphatase family. PP-1 subfamily. View All» Product Name: Anti-PP-1B View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»
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