货号：07-1392

品牌：Merck Millipore

规格：100UL

目录价：￥4438.00

市场价格：￥3772.30

会员价格：￥3550.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Rab40C Antibody | 07-1392 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Detects Rab40C View All» Molecular Weight: 31 kDa View All» Immunogen: Full-length His-tagged Rab40C recombinant protein (mouse). View All» Background Information: The Rab family of proteins are a member of the Ras superfamily of small G-Proteins. At least 60 isoforms have been identified. These GTPases are primarily involved in regulating distinct steps in vesicle trafficking by regulating the dynamic assembly and disassembly of the multi-protein scaffolds that are involved in vesicle trafficking. In its active, GTP-bound state, the Rab protein recruits effector proteins to the membrane. Rabs lack intrinsic GTPase hydrolysis activity and thus rely on guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs) to regulate their activity. Through these effectors, they regulate vessicle formation and movement. Rab4 and Rab11 are involved in internalization, sorting and transport to lysosomes or recycling of several membrane proteins, including GPCRs, GLUT-4, Aquaporin-2 or the H+/K+ ATPase. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Human, Mouse, and Rat. Other species have not been tested. View All» Application Notes: Western Blot Analysis :Immunohistochemistry Analysis:Immunohistochemistry (IHC) staining of mouse epithelium cells during lung development. Antibody was used at a 1:1,000 dilution and stained overnight at 4°C. 10X amplification. View All» Quality Assurance: Western Blot Analysis: This lot detected Rab40C at 1:1,000 dilution in Rat lung lysate resolved via SDS-PAGE and transferred to PVDF View All» Purification Method: Unpurified View All» Presentation: Rabbit Serum View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt. Store at -80°C for longer term storage. Avoid repeated freeze/thaws.Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. View All» UniProt Number: Q96S21 View All» Entrez Gene Number: NP_066991 View All» Gene Symbol:
  • RARL

  • RASL8C

  • RAB40C
    View All» Alternate Names:
    • RAB40C, member RAS oncogene family

    • RAR (RAS like GTPASE) like

    • RAR like

    • RAS-like GTPase

    • RAS-like, family 8, member C

    • Rar-like protein

    • Ras-like protein family member 8C

    • SOCS box-containing protein RAR3
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» UniProt Summary: Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Pathway: Protein modification; protein ubiquitination.Subunit structure: Component of the probable SCF-like ECS(RAB40C) E3 ubiquitin-protein ligase complex which contains CUL5, RNF7/RBX2, Elongin BC complex and RAB40C. Interacts with CUL5, RNF7, TCEB1 and TCEB2. Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic sidePotential. Domain: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes By similarity.Sequence similarities: Belongs to the small GTPase superfamily. Rab family.Contains 1 SOCS box domain View All» Product Name: Anti-Rab40C View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μL View All» Format: Unpurified View All» Host: Rabbit View All»
        © 金山科研平台是专业的授权总代理区域代理经销平台。
        © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
        © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
        © 本文地址：https://16ao.com/thread-134698.htm
        © Merck Millipore代理07-1392 Anti-Rab40C Antibody;store at -20℃，产品报价联系微信jinshanbio