金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Gln33-Asp393 (Ile379Val) (mature) & Pro166-Asp393 (Ile379Val) (C-terminus peptide), both with a C-terminal 6-His tag & Gln33-Asp165 (N-terminus peptide) Accession #:Q7TQ32 N-terminal Sequence Analysis:Gln33 (mature & N-terminus peptide) & Pro166 (C-terminus peptide) Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:40 kDa (mature), 14 kDa (N-terminus peptide), 26 kDa (C-terminus peptide) SDS-PAGE:57 kDa, 20 kDa and 38 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.Immobilized rhBMP-4 at 1µg/mL (100 µL/well) can bind rmRGM-C with a linear range of 0.016-1µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: RGM-C/Hemojuvelin Long Name: Repulsive Guidance Molecule C Aliases: DL-M; Hemojuvelin; HFE2; HJV; JH Entrez Gene IDs: 148738 (Human); 69585 (Mouse); 310681 (Rat) Background: RGMs The repulsive guidance molecule (RGM) family of molecules contains three uniquely structured GPI-linked glycoproteins that participate in a variety of activities. Termed RGM-A, -B and -C, they are 40-45 kDa in size, show generally nonoverlapping fetal expression patterns, and serve as BMP-4 receptors. RGM-A and -C are plasma membrane bound, while RGM-B is generally microsomal in location. RGM-A and -B are associated with neurons, while RGM-C regulates skeletal muscle and hepatocyte function.