金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Glu2-Glu222, with an N-terminal Met and 6-His tag Accession #:P70202 N-terminal Sequence Analysis:Met Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:26 kDa SDS-PAGE:29 kDa, reducing conditions Activity:Measured by its ability to inhibit carboxypeptidase A1 cleavage of the colorimetric peptide substrate Ac-Phe-Thiaphe-OH in the presence of 5,5’Dithio-bis (2-nitrobenzoic acid) (DTNB). Edwards, K.M. et al. (1999) J. Biol. Chem. 274:30468.The IC₅₀ value is <2.0 nM, as measured under thedescribed conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris, NaCl and Glycerol.See Certificate of Analysis for details. Molecule Information: Latexin Aliases: ECI; LXN; TCI Entrez Gene IDs: 56925 (Human); 17035 (Mouse); 59073 (Rat) Background: Latexin Latexin, also known as tissue carboxypeptidase inhibitor, is the only mammalian carboxypeptidase inhibitor identified so far. Latexin is a marker of neurons in the lateral neocortex of the developing brain and is also highly expressed in mast cells and macrophages. It is induced in acute pancreatitis and lung inflammatory disease and is able to inhibit specific pancreatic and mast cell carboxypeptidases.