金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Gly49-Asp171 (N-terminus chain) & Pro172-Ser414 (C-terminus chain), with a C-terminal 6-His tag Accession #:Q7TQ33 N-terminal Sequence Analysis:Gly49 (N-terminus chain) & Pro172 (C-terminus chain) Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:13.3 kDa (N-terminus chain), 27.8 kDa (C-terminus chain) SDS-PAGE:20 kDa and 27 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.Immoblized rhBMP-4 at 1 µg/mL (100 µL/well) can bind rmRGM-B with a linear range of 0.016-1µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: RGM-B Long Name: Repulsive Guidance Molecule B Aliases: Dragon Entrez Gene IDs: 285704 (Human); 68799 (Mouse) Background: RGMs The repulsive guidance molecule (RGM) family of molecules contains three uniquely structured GPI-linked glycoproteins that participate in a variety of activities. Termed RGM-A, -B and -C, they are 40-45 kDa in size, show generally nonoverlapping fetal expression patterns, and serve as BMP-4 receptors. RGM-A and -C are plasma membrane bound, while RGM-B is generally microsomal in location. RGM-A and -B are associated with neurons, while RGM-C regulates skeletal muscle and hepatocyte function.