货号：07-1224

品牌：Merck Millipore

规格：100Ug

目录价：￥4438.00

市场价格：￥3772.30

会员价格：￥3550.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PP6C Antibody | 07-1224 View All» Replaces: 07-1224 is a recommended replacement for AB4091 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Recognizes the catalytic subunit of Protein Phosphatase 6, MW ~33kDa. View All» Molecular Weight: Recognizes the catalytic subunit of Protein Phosphatase 6 (PP6), MW ~33kDa. View All» Immunogen: The immunogen used to the purified peptide conjugated to KLH corresponding to the sequence NH2-Cys-Ala-Val-Pro-Asp-Ser-Glu-Arg-Val-Ile- Pro-Pro-Arg-Thr-Thr-Thr-Pro-Tyr-COOH. View All» Isotype: IgG View All» Background Information: This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. View All» Species Reactivity:

• Bovine

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Bovine; Human; Mouse; Rat View All» Application Notes: Immunoprecipitation: A previous lot of this antibody was used in immunoprecipitation at a dilution of 10-20 µg/mL. Immunohistochemistry(paraffin):Optimal Staining of PP6 Polyclonal Antibody:Human TestisPP6 staining of round spermatids in normal humantestis, tissue pretreated with citrate buffer, pH 6.0.Antibody was diluted 1:100, using IHC-Select®detection with HRP-DAB. View All» Control: Jurkat Cell Lysate View All» Quality Assurance: Routinely evaluated by Western Blot on Jurkat lysates.Western Blot Analysis: 1:500 dilution of this lot detected PP6C on 10 μg of Jurkat lysates. View All» Presentation: Purified rabbit polyclonal IgG in buffer containing PBS with 0.08% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt.Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: O00743 View All» Entrez Gene Number: NM_002721.3 View All» Gene Symbol:
  • PPP6C

  • PP6

  • PPP6

  • EC 3.1.3.16
    View All» Alternate Names:
    • H.sapiens mRNA for protein phosphatase 6

    • Serine/threonine-protein phosphatase 6

    • Protein phosphatase 6, catalytic subunit

    • Serine/threonine protein phosphatase catalytic subunit
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunoprecipitation

      • Immunohistochemistry (Paraffin)
        View All» Entrez Gene Summary: This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. The N-terminal domain of this protein restricts G1 to S phase progression in cancer cells. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X. View All» UniProt Summary: FUNCTION: SwissProt: O00743 # May function in cell cycle regulation.COFACTOR: Binds 1 iron ion per subunit (By similarity). & Binds 1 manganese ion per subunit (By similarity).SIZE: 305 amino acids; 35144 Da SUBCELLULAR LOCATION: Cytoplasm (By similarity).TISSUE SPECIFICITY: Highest expression levels in testis, heart, and skeletal muscle and lowest in placenta, lung and kidney.SIMILARITY: SwissProt: O00743 ## Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily. View All» Product Name: Anti-PP6C Antibody | 07-1224 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Rabbit View All»
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