货号：07-1223

品牌：Merck Millipore

规格：100Ug

目录价：￥4899.00

市场价格：￥4164.15

会员价格：￥3919.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Protein Phosphatase 2 C α/β Antibody | 07-1223 View All» Replaces: AB4090 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Recognizes the alpha/beta regulatory subunit isotype of protein phosphatase 2C (PP2C). PP 2C alpha/beta polyclonal antibody binds a 44-46 kDa protein. View All» Molecular Weight: Approx. 46 kDa View All» Immunogen: Purified peptide conjugated to KLH. View All» Background Information: PP-2 C α/β is heterodimer located in the mitochondrial matrix. Within the pyruvate dehydrogenase complex, PP-2 C α/β serves to catalyze the dephosphorylation and concomitant reactivation of the E1 component’s alpha subunit. Mutations occurring in the PDP1 gene are the cause of a disease known as pyruvate dehydrogenase deficiency (PDP deficiency), which leads to neurological dysfunction from lactic acidosis. View All» Species Reactivity:

• Bovine

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Proven to react with human and rat. Expected to react with mouse based on sequence homology. View All» Control: L6 Cell Lysate View All» Quality Assurance: Evaluated by Western Blot in L6 cell lysates.Western Blot Analysis: 1:500 dilution of this lot detected PP-2 C ALPHA/BETA on 10 ug of L6 lysates. View All» Purification Method: Protein Purified View All» Presentation: Purified immunoglobulin in phosphate buffered saline with 0.08% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q9P0J1 View All» Entrez Gene Number: Q9P0J1 View All» Gene Symbol:
  • PPM2C

  • PDPC

  • PDP1

  • FLJ32517

  • PDH

  • PDP

  • MGC119646

  • EC 3.1.3.43
    View All» Alternate Names:
    • Protein phosphatase 2C

    • Pyruvate dehydrogenase

    • Pyruvate dehydrogenase phosphatase, catalytic subunit 1

    • Lipoamide-phosphatase 1, mitochondrial precursor

    • Protein phosphatase 2C, magnesium-dependent, catalytic subunit

    • Pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase

    • Pyruvate dehydrogenase phosphatase
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: SwissProt: Q9P0J1 # Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (By similarity).COFACTOR: Binds 2 magnesium ions per subunit (By similarity).SIZE: 537 amino acids; 61054 Da SUBUNIT: Heterodimer of a catalytic subunit and a FAD protein of unknown function (By similarity).SUBCELLULAR LOCATION: Mitochondrion matrix (By similarity).DISEASE:SwissProt: Q9P0J1 # Defects in PDP1 are the cause of pyruvate dehydrogenase phosphatase deficiency (PDP deficiency) [MIM:608782]. PDP deficiency results in lactic acidosis leading to neurological dysfunction.SIMILARITY: SwissProt: Q9P0J1 ## Belongs to the PP2C family. View All» Product Name: Anti- Protein Phosphatase 2 C α/β View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Rabbit View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://16ao.com/thread-134599.htm
      © Merck Millipore代理07-1223 Anti-Protein Phosphatase 2 C α/β Antibody;store at -20℃，产品报价联系微信jinshanbio