货号：07-103

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-IGF2 mRNA-binding protein 2 Antibody | 07-103 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes IGF2 mRNA-binding protein 2. View All» Molecular Weight: 62 kDa. Predicted to cross-react with all the Isoforms of IGF2 mRNA-binding protein 2 View All» Epitope: Internal Domain View All» Immunogen: KLH-conjugated linear peptide corresponding to human IGF2 mRNA-binding protein 2 at and around the internal domain. View All» Background Information: The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]. View All» Species Reactivity:

• Human

• Chimpanzee

• Bovine
  View All» Species Reactivity Note: Reacts with human. Predicted to react with chimpanzee, Rhesus monkey, and cow based on 100% sequence homology. View All» Application Notes: Western Blot (SNAP ID) Analysis: 4 µg/mL from a previous lot detected IGF2 mRNA-binding protein 2 on 10 µg of Hek293 lysate. View All» Control: Hek293 cell lysate View All» Quality Assurance: Evaluated by Western Blot in Hek293 cell lysate.Western Blot Analysis: 0.1 µg/mL of this antibody detected IGF2 mRNA-binding protein 2 on 10 µg of Hek293 lysate. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit serum in PBS with 0.09% azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9Y6M1 View All» Entrez Gene Number: NP_006539 View All» Gene Symbol:
  • IGF2BP2

  • IMP-2

  • IMP2

  • VICKZ2

  • p62
    View All» Alternate Names:
    • Hepatocellular carcinoma autoantigen p62

    • IGF-II mRNA-binding protein 2

    • IGF2 mRNA-binding protein 2

    • VICKZ family member 2

    • insulin-like growth factor 2 mRNA binding protein 2
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs. SUBUNIT STRUCTURE: Interacts with HNRPD. SUBCELLULAR LOCATION: Cytoplasm Probable. Note: Localizes at the connecting piece and the tail of the spermatozoa.TISSUE SPECIFICITY: Expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia and semen (at protein level). Expressed in testicular cancer (at protein level). Expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. Detected in fetal liver, fetal ovary, gonocytes and interstitial cells of the testis. INVOLVEMENT IN DISEASE: Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.SEQUENCE SIMLARITIES: Belongs to the RRM IMP/VICKZ family.Contains 4 KH domains.Contains 2 RRM (RNA recognition motif) domains. View All» Product Name: Anti-IGF2 mRNA-binding protein 2 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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