货号：06-351

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-14-3-3 β/ζ Antibody | 06-351 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: beta and zeta isoforms View All» Molecular Weight: 27kDa View All» Immunogen: peptide (ELVQKAKLAEQA) corresponding to the beta and zeta isoforms of 14-3-3 View All» Isotype: IgG View All» Species Reactivity:

• Insect

• Mammals
  View All» Quality Assurance: routinely evaluated by immunoblot on RIPA lysate prepared from humans A431 epidermoid, mouse 3T3 fibroblast, rat L6 skeletal fibroblast, chinese hamster ovary cells or rabbit brain cytosol View All» Purification Method: Protein A chromatography View All» Presentation: PBS, 30% glycerol View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P31946 View All» Entrez Gene Number: NM_003404 View All» Gene Symbol:
  • YWHAB

  • GW128

  • KCIP-1

  • HS1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P31946 # Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.SIZE: 246 amino acids; 28082 Da SUBUNIT: Homodimer. Interacts with SSH1.SUBCELLULAR LOCATION: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.PTM: Isoform alpha differs from isoform beta in being phosphorylated (By similarity). & Isoform Short contains a N-acetylmethionine at position 1 (By similarity).SIMILARITY: SwissProt: P31946 ## Belongs to the 14-3-3 family. View All» Brand Family: Upstate View All» Product Name: Anti-14-3-3 β/ζ Antibody | 06-351 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Rabbit View All»
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