货号：06-1376

品牌：Merck Millipore

规格：100UL

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-SLBP Antibody | 06-1376 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Antibody recognizes SLBP. View All» Molecular Weight: 38 kDa View All» Epitope: C-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human SLBP. View All» Background Information: The SLPB gene (stem-loop binding protein) encodes a protein that binds to the stem-loop structure of replication-dependent histone pre-mRNAs. Histone mRNA lack a polyadenylation signal. Consequently, the interaction of this protein with histone pre-mRNA contributes to efficient 3' end processing by stabilizing the complex between the pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP). Expression of this protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Reacts with Human and Mouse. Predicted to react with Rat based on sequence homology. View All» Application Notes: Immunocytochemistry:Representative lot data.Confocal fluorescent analysis of NIH/3T3 cells using 06-1376 (Red). Actin filaments have been labeled with AlexaFluor®488 -Phalloidin (Green). Nucleus is stained with DAPI (Blue). This antibody positively stains cytoplasm and nucleus. View All» Control: C2C12 cell lysates. View All» Quality Assurance: Evaluated by Western Blotting in C2C12 cell lysates.Western Blotting Analysis: A 1:1000 dilution of this antibody detected SLBP in C2C12 cell lysates. View All» Purification Method: Unpurified View All» Presentation: Serum in buffer containing 0.05% sodium azide View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P97440 View All» Entrez Gene Number: NM_009193 View All» Gene Symbol: SLBP View All» Alternate Names:
  • Histone stem-loop-binding protein

  • hairpin binding protein

  • histone binding protein 2

  • histone stem-loop binding protein

  • stem-loop (histone) binding protein

  • stem-loop binding protein

  • HBP

  • Histone RNA hairpin-binding protein
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunocytochemistry
      View All» Entrez Gene Summary: This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1. [provided by RefSeq] View All» UniProt Summary: FUNCTION:Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3' end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP). Could play an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression By similarity.SUBUNIT STRUCTURE:: Monomer. SLBP/pre-mRNA complex interacts with ZNF473. Interacts with MIF4GD By similarity.SUBCELLULAR LOCATION:: Cytoplasm. Nucleus. Note: Polyribosome-associated.TISSUE SPECIFICITY: Widely expressed.SEQUENCE SIMILARITIES: Belongs to the SLBP family. View All» Product Name: Anti-SLBP View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://16ao.com/thread-134315.htm
      © Merck Millipore代理06-1376 Anti-SLBP Antibody;store at -20℃，产品报价联系微信jinshanbio