货号：06-1081

品牌：Merck Millipore

规格：

目录价：￥3433.00

市场价格：￥2918.05

会员价格：￥2746.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-IL-26 Antibody | 06-1081 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes IL-26 near the C-terminus. This antibody was used on ELISA to test specificity against immunizing peptide. View All» Molecular Weight: ~17 kDa observed.~20 kDa calculated molecular weight. View All» Epitope: Near the C-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to human IL-26 near the C-terminus. View All» Background Information: Interleukin 26 (IL-26) is a homodimer cytokine belonging to the IL-10 family that is expressed in certain herpesvirus-transformed T cells but not in primary stimulated T cells. Two such T cells are Th1 and Th17. IL-26 signals through a receptor complex comprising two distinct proteins called IL-20 receptor 1 and IL-10 receptor 2. By signaling through this receptor complex, IL-26 induces rapid phosphorylation of the transcription factors STAT1 and STAT3, which enhance IL-10 and IL-8 secretion and as expression of the CD54 molecule on the surface of epithelial cells. IL-26's function in human disease is unknown, however research has found that IL-26 expression is up-regulated in active Crohn's disease, and therefore may play an active role along with Th17 cells in various autoimmune diseases. View All» Species Reactivity:

• Human

• Monkey
  View All» Species Reactivity Note: Tested to react with human. Predicted to react with monkey based on 100% sequence homology. View All» Application Notes: Flow Cytometry Analysis: 5 µg from a previous lot detected IL-26 in lymphocytes from human PBMC's.Western Blot (SNAP ID) Analysis: 1 µg/mL from a previous lot detected recombinant human IL-26. View All» Control: Recombinant human Interleukin 26 (IL-26). View All» Quality Assurance: Evaluated by Western Blot on recombinant human IL-26.Western Blot Analysis: 0.1 µg/mL of this antibody detected recombinant human IL-26. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit polyclonal in PBS with 0.09% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9NPH9 View All» Entrez Gene Number: NP_060872 View All» Gene Symbol:
  • IL26

  • AK155

  • IL-26
    View All» Alternate Names:
    • AK155 protein

    • interleukin 26
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Flow Cytometry
        View All» Entrez Gene Summary: This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq] View All» UniProt Summary: SUBUNIT STRUCTURE: Homodimer.SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells.INDUCTION: By Herpesvirus saimiri infection.SEQUENCE SIMILARITIES: Belongs to the IL-10 family. View All» Product Name: Anti-IL-26 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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