货号：06-1064

品牌：Merck Millipore

规格：200UL

目录价：￥4438.00

市场价格：￥3772.30

会员价格：￥3550.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Itk/Emt/Tsk Antibody | 06-1064 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Recognizes Itk/Emt/Tsk, Mr ~72 kDa. View All» Molecular Weight: 72 kDa View All» Immunogen: Recombinant protein.Itk/Emt/Tsk-GST fusion protein (Itk/Emt/Tsk amino acid residues 1-270) spanning the PH, SH3 domains and a small portion of the SH2 domain; bound to nitrocellulose paper. View All» Background Information: Itk is a T cell signaling protein. The Tec family of non-receptor tyrosine kinases is composed of six proteins designated Tec, Itk (also known as Emt or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain pleckstrin homology (PH) and Tec homology (TH) domains in their amino termini. Itk associates with CD28 and becomes activated subsequent to CD28 ligation. View All» Species Reactivity:

• Human

• Mouse
  View All» Species Reactivity Note: Human. Predicted to cross-react with mouse based on 100% sequence homology. View All» Control: Jurkat cell lysates View All» Quality Assurance: Routinely evaluated by western blot on Jurkat cell lysate.Western Blot Analysis:0.05-1 µg/mL of this lot detected Itk/Emt/Tsk in 10 µg of a Jurkat cell lysate. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit polycloncal in buffer containing PBS with 0.05% sodium azide and 50% glycerol. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt. For maximum recovery of the product, centrifuge the original vial and prior to removing the cap. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage. View All» UniProt Number: Q08881 View All» Entrez Gene Number: NP_005537 View All» Gene Symbol:
  • EC 2.7.10.2

  • EMT

  • LYK

  • MGC126257

  • MGC126258

  • PSCTK2
    View All» Alternate Names:
    • IL2-inducible T-cell kinase

    • Kinase EMT

    • T-cell-specific kinase

    • Tyrosine-protein kinase Lyk

    • homolog of mouse T-cell itk/tsk

    • tyrosine-protein kinase ITK/TSK
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunoprecipitation
        View All» Entrez Gene Summary: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq] View All» Product Name: Anti-Itk/Emt/Tsk View All» Concentration: 0.125 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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        © Merck Millipore代理06-1064 Anti-ITK/EMT/TSK Antibody;store at -20℃，产品报价联系微信jinshanbio