货号：06-1001

品牌：Merck Millipore

规格：EA

目录价：￥3348.00

市场价格：￥2845.80

会员价格：￥2678.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Torsin-1A-interacting protein 1 Antibody | 06-1001 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes Torsin-1A-interacting protein 1. View All» Molecular Weight: There are at least half a dozen splice variants, the primary band being at 67 kDa. View All» Epitope: Lumenal View All» Immunogen: KLH- Conjugated - Linear Peptide corresponding to the lumenal portion of human Torsin-1A-interacting protein 1. View All» Background Information: Torsin-1A-interacting protein 1, also known as lamina associated polypeptide 1B (LAP1B), is a protein encoded by the TOR1AIP1 gene. As suggested by its name, this protein interacts with torsin A and is implicated in the the disease torsion A dystonia. This protein is a type II integral membrane protein with a nuclear N-terminus and a single transmembrane domain. It is known to bind to A- and B-type lamins and has a possible role in membrane attachment and assembly of the nuclear lamina. A number of splice variants are known to exist. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with human. Rat (75% sequence homology), Mouse (76% sequence homology) View All» Application Notes: Western Blot (SNAP ID) Analysis: 1 µg/ml of this antibody detected Torsin-1A-interacting protein 1 on 10 µg of HeLa cell lysate.Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected Torsin-1A-interacting protein 1 in HeLa and A431 cells. View All» Control: HeLa cell lysate View All» Quality Assurance: Evaluated by Western Blot in HeLa cell lysate.Western Blot Analysis: 0.5 µg/ml of this antibody detected Torsin-1A-interacting protein 1 on 10 µg of HeLa cell lysate. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q5JTV8 View All» Entrez Gene Number: NP_056417 View All» Gene Symbol:

• TOR1AIP1

• LAP1B

• MGC3413

• FLJ13142

• DKFZp586G011

• RP11-533E19.1

• TOR1AIP1
  View All» Alternate Names:
  • associated polypeptide 1B

  • lamina-associated polypeptide 1B

  • torsin A interacting protein 1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunocytochemistry
      View All» UniProt Summary: FUNCTION: Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina By similarity.SUBUNIT STRUCTURE: Interacts with TOR1A. SUBCELLULAR LOCATION: Nucleus inner membrane; Single-pass membrane protein By similarity. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. SEQUENCE SIMILARITIES: Belongs to the TOR1AIP family. View All» Product Name: Anti-Torsin-1A-interacting protein 1 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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