货号：05-916

品牌：Merck Millipore

规格：100UL

目录价：￥5666.00

市场价格：￥4816.10

会员价格：￥4532.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-P-Cadherin Antibody, clone 6A9 | 05-916 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes P-Cadherin View All» Molecular Weight: Mr 120kDa View All» Immunogen: P-Cadherin extracellular domain purified from A431 cell membranes. View All» Species Reactivity: Human View All» Quality Assurance: Routinely evaluated by immunoblot on A431 cell lysates. View All» Purification Method: Ascites View All» Storage Conditions: 2 years at -20°C from date of shipment View All» UniProt Number: P22223 View All» Entrez Gene Number: NM_001793 View All» Gene Symbol:

• CDH3

• P-cadherin

• Placental-cadherin

• HJMD

• CDHP

• PCAD
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunoprecipitation

  • Western Blotting

  • Immunocytochemistry
    View All» Entrez Gene Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. View All» UniProt Summary: FUNCTION: SwissProt: P22223 # Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.SIZE: 829 amino acids; 91418 Da SUBUNIT: Interacts with CDCP1.SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.TISSUE SPECIFICITY: Expressed in some normal epithelial tissues and in some carcinoma cell lines.DISEASE: SwissProt: P22223 # Defects in CDH3 are the cause of hypotrichosis with juvenile macular dystrophy (HJMD) [MIM:601553]. HJMD is a rare autosomal recessive disorder characterized by early hair loss heralding severe degenerative changes of the retinal macula and culminating in blindness during the second to third decade of life. & Defects in CDH3 are the cause of EEM syndrome [MIM:225280]; also known as ectodermal dysplasia, ectrodactyly, and macular dystrophy or Albrectsen-Svendsen syndrome or Ohdo- Hirayama-Terawaki syndrome.SIMILARITY: SwissProt: P22223 ## Contains 5 cadherin domains. View All» Brand Family: Upstate View All» Product Name: Anti-P-Cadherin Antibody, clone 6A9 | 05-916 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
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