货号：05-822

品牌：Merck Millipore

规格：100UL

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Rho (-A Antibody, -B, -C), clone 3L74 | 05-822 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes Rho (-A, -B, -C) View All» Molecular Weight: Mr 22kDa View All» Immunogen: KLH-conjugated, synthetic peptide (SYPDTDVILMCFSIDSPDSLENKK) corresponding to amino acids 73-94 of human Rho (-A, -B, -C), with two terminal lysines added to increase peptide solubility View All» Isotype: IgG View All» Species Reactivity:

• Human

• Rat
  View All» Species Reactivity Note: Broad species cross-reactivity expected based on sequence homology View All» Quality Assurance: routinely evaluated by immunoblot on modified RIPA lysates from HL-60 cells View All» Purification Method: Protein A purfied View All» Storage Conditions: Stable for 2 years at -20°C from date of shipment View All» UniProt Number: P61586 View All» Entrez Gene Number: NM_001664 View All» Gene Symbol:
  • RHOA

  • RHO12

  • Rho12

  • RhoA

  • RHOH12

  • H12

  • ARHA

  • ARH12
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: SwissProt: P61586 # Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. May be an activator of PLCE1.COFACTOR: Magnesium.SIZE: 193 amino acids; 21768 Da SUBUNIT: Binds PRKCL1, ROCK1 and ROCK2. Interacts with ARHGEF3, NET1 and RTKN. Interacts with PLCE1 and AKAP13.SUBCELLULAR LOCATION: Membrane; Lipid-anchor.DOMAIN: SwissProt: P61586 The basic-rich region is essential for yopT recognition and cleavage.PTM: Substrate for botulinum ADP-ribosyltransferase. & Cleaved by yopT protease when the cell is infected by some Yersinia pathogens. This removes the lipid attachment, and leads to its displacement from plasma membrane and to subsequent cytoskeleton cleavage.SIMILARITY: Belongs to the small GTPase superfamily. Rho family. View All» Brand Family: Upstate View All» Product Name: Anti-Rho (-A Antibody, -B, -C), clone 3L74 | 05-822 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rabbit View All»
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    © Merck Millipore代理05-822 Anti-Rho (-A, -B, -C) Antibody, clone 3L74, rabbit monoclonal;store at -20℃，产品报价联系微信jinshanbio