货号：05-779

品牌：Merck Millipore

规格：100UL

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Meis 1/2/3 Antibody, clone 9.2.7 | 05-779 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Meis1, Meis2, Meis3 and splice variants View All» Molecular Weight: Mr ~45-66kDa View All» Immunogen: MBP-conjugated fusion protein corresponding to amino acids 60-390 of mouse Meis1 View All» Isotype: IgG1 View All» Background Information: Hox, Pbx, and Meis families of transcription factors form heteromeric complexes and bind DNA through specific homeobox domains. Meis1, 2, and 3 are members of the TALE (three amino acid loop extension) family of homeodomain containing proteins. Meis1 binds to Hox and Pbx proteins to form complexes with distinct DNA-binding specificities. Like Hox and Pbx proteins, the overexpression of Meis1 in BHX-2 myeloid leukemias implies a role for this protein in oncogenesis. Two Meis related proteins, Meis2 and Meis3 (also designated Mrg1 and Mrg2, respectively), possess largely similar sequence identity with Meis1 and express in normal tissues as well as myeloid leukemias. In the pancreas, Meis2 preferentially associates with Pbx1, and together they associate with the pancreas specific homeodomain factor, Pdx1, to repress Pdx1-induced transcriptional activation. View All» Species Reactivity:

• Human

• Mouse
  View All» Control: K562 nuclear extract View All» Quality Assurance: routinely evaluated by immunoblot on nuclear extract from K562 cells View All» Purification Method: Ascites View All» Presentation: mouse ascites IgG1 containing 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: O14770 View All» Entrez Gene Number: NM_170677 View All» Gene Symbol:
  • MEIS2

  • MGC2820

  • MRG1

  • HsT18361
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting

    • Immunohistochemistry
      View All» Entrez Gene Summary: This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene. View All» UniProt Summary: SIZE: 477 amino acids; 51790 Da SUBCELLULAR LOCATION: Nucleus (Probable).TISSUE SPECIFICITY: Expressed in various tissues. In hematopoietic tissues, the lymphoid organs express high levels of MEIS2. Also expressed in some regions of the brain, such as the putamen.SIMILARITY: SwissProt: O14770 ## Belongs to the TALE/MEIS homeobox family. & Contains 1 homeobox DNA-binding domain. View All» Brand Family: Upstate View All» Product Name: Anti-Meis 1/2/3 Antibody, clone 9.2.7 | 05-779 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://16ao.com/thread-134035.htm
      © Merck Millipore代理05-779 Anti-Meis 1/2/3 Antibody, clone 9.2.7;store at -20℃，产品报价联系微信jinshanbio