货号：05-639

品牌：Merck Millipore

规格：

目录价：￥3990.00

市场价格：￥3391.50

会员价格：￥3192.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-14-3-3γ Antibody, clone CG31-2B6 | 05-639 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: 14-3-3 gamma; does not cross-react with other 14-3-3 isoforms View All» Molecular Weight: 30kDa View All» Immunogen: GST fusion protein corresponding to full-length human 14-3-3 gamma View All» Clone: CG31-2B6 View All» Isotype: IgG1 View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Quality Assurance: routinely evaluated by immunoblot on RIPA lysate from 3T3/A31 cells View All» Purification Method: Protein A chromatography View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P61981 View All» Entrez Gene Number: NM_012479 View All» Gene Symbol:
  • YWHAG

  • KCIP-1

  • 14-3-3GAMMA
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. View All» UniProt Summary: FUNCTION: SwissProt: P61981 # Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.SIZE: 247 amino acids; 28303 Da SUBUNIT: Homodimer. Interacts with RAF1 and SSH1.SUBCELLULAR LOCATION: Cytoplasm (By similarity).TISSUE SPECIFICITY: Highly expressed in brain, skeletal muscle, and heart.PTM: Phosphorylated by various PKC isozymes.SIMILARITY: SwissProt: P61981 ## Belongs to the 14-3-3 family. View All» Brand Family: Upstate View All» Product Name: Anti-14-3-3γ Antibody, clone CG31-2B6 | 05-639 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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