货号：05-543

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Eck/EphA2 Antibody, clone B2D6 | 05-543 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes Eck/EphA2/Mpk-5. View All» Molecular Weight: 140 kDa View All» Immunogen: Native Epithelial Cell Kinase (Eck, also referred to as EphA2 and Mpk-5), isolated by purification of phosphotyrosine-containing proteins from ras-transformed human breast epithelial cells View All» Clone: B2D6 View All» Isotype: IgG View All» Species Reactivity: Human View All» Application Notes: Not recommended for WB. View All» Control: Expressed in most tissue, MCF-7 cell lysate View All» Quality Assurance: routinely evaluated by immunoprecipitation of EphA2 from MCF-7 RIPA lysate, subsequent immunoblotting performed using Anti-Eck/EphA2, clone D7 antibody (Catalog #05-480) View All» Purification Method: Unpurified View All» Presentation: Protein G Purified immunoglobulin in Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative. View All» Storage Conditions: Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P99999 View All» Entrez Gene Number: NM_004431 View All» Gene Symbol:

• CYCS

• CYC

• HCS
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunoprecipitation View All» Entrez Gene Summary: This gene encodes cytochrome c, a component of the electron transport chain in mitochondria. The heme group of cytochrome c accepts electrons from the b-c1 complex and transfers electrons to the cytochrome oxidase complex. Cytochrome c is also involved in initiation of apoptosis. Upon release of cytochrome c to the cytoplasm, the protein binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Many cytochrome c pseudogenes exist, scattered throughout the human genome. View All» UniProt Summary: FUNCTION: SwissProt: P99999 # Plays a role in apoptosis. Suppression of the anti- apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.SIZE: 105 amino acids; 11749 Da SUBCELLULAR LOCATION: Mitochondrion matrix.PTM: Binds 1 heme group per subunit.SIMILARITY: SwissProt: P99999 ## Belongs to the cytochrome c family. View All» Brand Family: Upstate View All» Product Name: Anti-Eck/EphA2 Antibody, clone B2D6 | 05-543 View All» Concentration: Variable View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μL View All» Format: Ascites View All» Host: Mouse View All»
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