货号：05-517

品牌：Merck Millipore

规格：200Ug

目录价：￥6742.00

市场价格：￥5730.70

会员价格：￥5393.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1 | 05-517 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes PTH/PTHrP receptor and the receptor dimer. View All» Molecular Weight: 80 kDa; receptor dimer at 160 kDa View All» Immunogen: Synthetic peptide corresponding to amino acids 146-169 of the human PTH/PTHrP (parathyroid hormone/parathyroid hormone related protein) receptor (RRCDRNGSWELVPGHNRTWANYSE). View All» Clone: 3D1.1 View All» Isotype: IgG1κ View All» Species Reactivity:

• Human

• Mouse

• Pig
  View All» Control: Kidney Tissue View All» Quality Assurance: Routinely evaluated by immunoblot on RIPA lysates of 3T3-L1 pre-adipose fibroblasts View All» Purification Method: Protein G purfied View All» Presentation: Protein G Purified immunoglobulin in Immunoaffinity Purified immunoglobulin in 0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% View All» Storage Conditions: Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P12272 View All» Entrez Gene Number: NM_000315 View All» Gene Symbol:
  • PTHLH

  • PTHRP

  • osteostatin

  • PTHrP

  • MGC14611

  • PTHR

  • 107-139).

  • PLP

  • HHM

  • PTH-rP
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. View All» UniProt Summary: FUNCTION: SwissProt: P12272 # Osteostatin is a potent inhibitor of osteoclastic bone resorption.SIZE: 177 amino acids; 20194 Da SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Secreted.TISSUE SPECIFICITY: Ubiquitous. Also expressed in the mammary gland.PTM: There are 3 principal secretory forms, called PTHrP[1-36], PTHrP[38-94], and osteostatin (PTHrP[107-139]) arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.DISEASE:SwissProt: P12272 # Produced by many tumors from patients with HHM (humoral hypercalcemia of malignancy).SIMILARITY: SwissProt: P12272 ## Belongs to the parathyroid hormone family. View All» Brand Family: Upstate View All» Product Name: Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1 | 05-517 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 200 μg View All» Format: Purified View All» Host: Mouse View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://16ao.com/thread-133832.htm
      © Merck Millipore代理05-517 Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1;store at -20℃，产品报价联系微信jinshanbio