货号：MABT138

品牌：Merck Millipore

规格：100Ug

目录价：￥4497.00

市场价格：￥3822.45

会员价格：￥3597.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Ahi-1 (Jouberin) Antibody, clone C-mAh1-1 M5 | MABT138 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~120 kDa observed View All» Immunogen: Recombinant protein corresponding to mouse Ahi-1 (Jouberin). View All» Clone: C-mAh1-1 M5 View All» Isotype: IgG1κ View All» Background Information: Abelson helper integration site 1 (Ahi-1) is an abundant brain protein which may function as an adaptor protein mediating various cellular processes. It contains multiple SH3 binding sites and WD40-repeats, structures known to enable protein-protein interactions and facilitate metabolic functions. The latter is supported by the finding that mutations in Ahi-1 contribute to type 2 diabetes. Ahi-1 also plays an important role in oncogenesis, possibly through its interaction with BCR, ABL, and Jak2. Mutations in the Ahi-1 gene have been linked to the autosomal recessive brain disorder Joubert syndrome. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with Mouse. View All» Application Notes: Immunohistochemistry Analysis: A representative lot from an independent laboratory detected Ahi-1 (Jouberin) in stably transfected IMCD3 cells (Hsiao, Y. C., et al. (2009). Hum Mol Genet. 18(20):3926-3941.). View All» Control: Mouse brain tissue lysate View All» Quality Assurance: Evaluated by Western Blot in mouse brain tissue lysate.Western Blot Analysis: 1 µg/mL of this antibody detected Ahi-1(Jouberin) in 10 µg of mouse brain tissue lysate. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8K3E5 View All» Entrez Gene Number: NP_080479 View All» Gene Symbol: Ahi1 View All» Alternate Names:

• Jouberin

• Abelson helper integration site 1 protein

• AHI-1
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunoprecipitation
    View All» Product Name: Anti-Ahi-1 (Jouberin), clone C-mAh1-1 M5 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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