货号：MABS22

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Mob3 Antibody, clone 16E2 | MABS22 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~ 26 kDa observed. UniProtKB/Swiss-Prot Q9Y3A3 (MOBL3_HUMAN) entry describes 2 isoforms produced by alternative splicing: Isoform 1 at 26.032 kDa, and Isoform 2 at 22.318 kDa. View All» Immunogen: KLH-conjugated linear peptide corresponding to human Mob3. View All» Clone: 16E2 View All» Isotype: IgG1κ View All» Background Information: Mps one binder kinase activator-like 3 (Mob3) is a member of the MOB1/phoecin/preimplantation antigen family of proteins. Mob3 acts a binding protein, interacting with STRN, STRN3, and STRN4. It is a component in a complex comprised of MOBKL3, PPA2, and either STRN or STRN3. Studies have observed the phosphorylation of Mob3 on serine residues; however, the exact function of this protein is yet to be defined. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with human, mouse, and rat. View All» Control: HEK293 cell lysate View All» Quality Assurance: Evaluated by Western Blot in HEK293 cell lysate.Western Blot Analysis: 1:100,000 dilution of this antibody detected Mob3 on 10 µg of HEK293 cell lysate. View All» Purification Method: Unpurified View All» Presentation: Mouse monoclonal IgG1κ ascites containing 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: Q9Y3A3 View All» Entrez Gene Number: NP_056202 View All» Gene Symbol:
  • MOB3

  • Mob3

  • PREI3

  • 2C4D

  • CGI-95

  • MOB1
    View All» Alternate Names:
    • MOB1

    • Mps One Binder kinase activator-like 3 (yeast)

    • Mob1 homolog 3

    • Preimplantation protein 3

    • phocein

    • mps one binder kinase activator-like 3

    • Class II mMOB1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]. View All» UniProt Summary: SUBUNIT STRUCTURE: Binds STRN4 (by similarity). Binds STRN and STRN3. Part of a ternary complex containing MOBKL3, STRN and/or STRN3 and PPA2.SUBCELLULAR LOCATION: Cytoplasm › perinuclear region. Membrane; Peripheral membrane protein. Golgi apparatus › Golgi stack membrane; Peripheral membrane protein. Note: In a perinuclear punctate pattern. Associated with membranes and the Golgi stacks. PTM: Phosphorylated on serine residues. SEQUENCE SIMILARITIES: Belongs to the MOB1/phocein family.SEQUENCE CAUTION: The sequence AAP97221.1 differs from that shown. Reason: Erroneous initiation. The sequence CAB45697.1 differs from that shown. Reason: Frameshift at position 168. View All» Product Name: Anti-Mob3, clone 16E2 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
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