货号：MABN488

品牌：Merck Millipore

规格：100Ug

目录价：￥4439.00

市场价格：￥3773.15

会员价格：￥3551.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GABA(B)R2 Protein Antibody, clone N81/2 | MABN488 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the C-terminus of GABA(B)R2 Protein. This antibody does not cross react with GABA(B)R1. View All» Molecular Weight: ~105 kDa observed View All» Epitope: C-terminus View All» Immunogen: Recombinant protein corresponding to the C-terminus of rat GABA(B)R2 Protein. View All» Clone: N81/2 View All» Isotype: IgG1κ View All» Background Information: The inhibitory neurotransmitter, GABA, acts through two ligand-gated channels, GABA(A) and GABA(C) receptors and GABA(B), the latter of which acts through a G protein mechanism. GABA(B)R2 is one of the two G-protein coupled receptors for GABA(B) that acts as a heteromeric assembly with GABA(B)R1. These are 6 known subunits for the GABA Receptor (a, b, g, d, e and r). View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, and Rat. View All» Application Notes: Immunohistochemistry Analysis: A representative lot detected GABA(B)R2 Protein in rat hippocampus tissue.Western Blot Analysis: A representative lot from an independent laboratory detected GABA(B)R2 Protein in FMR1 knockout mice (Pacey, L. K., et al. 2011. J Pharmacol Exp Ther. 338(3):889-905.).Western Blot Analysis: A representative lot detected GABA(B)R2 in crude membrane preparations from RBM cells, and in WT but not in GABA(B)R2 knockout mice (Prof. J. Trimmer, University of California, Davis). View All» Control: Human brain tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human brain tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected GABA(B)R2 Protein in 10 µg of human brain tissue lysate. It is recommended to perform a membrane preparation for mouse and rat tissue samples to prevent the possible appearance of any uncharacterized bands. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: O88871 View All» Entrez Gene Number: NP_113990 View All» Gene Symbol:
  • Gabbr2

  • Gpr51
    View All» Alternate Names:
    • Gamma-aminobutyric acid type B receptor subunit 2

    • GABA-B receptor 2

    • GABA-B-R2

    • GABABR2

    • Gb2

    • G-protein coupled receptor 51
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Product Name: Anti-GABA(B)R2 Protein, clone N81/2 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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