货号:MABN301
品牌:Merck Millipore
规格:
目录价:¥4439.00
市场价格:¥3773.15
会员价格:¥3551.20
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Description:
Anti-Peroxiredoxin-5, (PRDX5) Antibody, clone 5 288 2F4 | MABN301
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Molecular Weight:
~17 kDa observed
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Immunogen:
Recombinant protein corresponding to human Peroxiredoxin-5.
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Clone:
5 288 2F4
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Isotype:
IgMκ
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Background Information:
Peroxiredoxin-5 (PRDX5) is a novel mammalian peroxiredoxin, belonging to the family of thiol-dependent peroxidases. It is structurally dissimilar from other peroxiredoxins in that it contains a conserved cysteine 47 residue at the N-terminus and a cysteine 151 residue at the C-terminus which form an intramolecular disulphide bridge and confers unique chemical characteristics to this enzyme. Peroxiredoxins protect cells from apoptosis induced by overexposure to endogenous or exogenous peroxides, such as peroxynitrites, hydrogen peroxide, and alkyl hydroperoxides. Peroxiredoxin 5 is widely expressed in various subcellular regions, including mitochondria, peroxisomes, nucleus, and cytosol.
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Species Reactivity:
Human
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Application Notes:
Western Blot Analysis: A 1:1,000 dilution from a representative lot detected Peroxiredoxin-5 (PRDX5) in human brain tissue lysate.Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Peroxiredoxin-5 (PRDX5) in human adrenal gland tissue.
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Control:
SH-SY5Y cell lysate
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Quality Assurance:
Evaluated by Western Blot in SH-SY5Y cell lysate.Western Blot Analysis: A 1:1,000 dilution of this antibody detected Peroxiredoxin-5 (PRDX5) in 10 µg of SH-SY5Y cell lysate.
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Purification Method:
Purified by ion-exchange chromatography.
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Presentation:
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
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Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
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UniProt Number:
P30044
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Entrez Gene Number:
NP_036226
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Gene Symbol:
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PRDX5
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ACR1
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SBBI10
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Alternate Names:
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Peroxiredoxin-5, mitochondrial
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Alu corepressor 1
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Antioxidant enzyme B166
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AOEB166
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Liver tissue 2D-page spot 71B
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PLP
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Peroxiredoxin V
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Prx-V
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Peroxisomal antioxidant enzyme
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TPx type VI
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Thioredoxin peroxidase PMP20
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Thioredoxin reductase
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
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Western Blotting
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Immunohistochemistry
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Product Name:
Anti-Peroxiredoxin-5, (PRDX5), clone 5 288 2F4
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Antibody Type:
Monoclonal Antibody
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Qty/Pk:
100 µL
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Format:
Purified
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Host:
Mouse
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