货号：MABF96

品牌：Merck Millipore

规格：100Ug

目录价：￥4592.00

市场价格：￥3903.20

会员价格：￥3673.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-TRAcP Antibody, clone 9C5 | MABF96 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: 36 kDa calculated View All» Immunogen: Full length purified protein corresponding to human TRAcP. View All» Clone: 9C5 View All» Isotype: IgG2bκ View All» Background Information: Tartrate-resistant acid phosphatase type 5 (TRAcP), also referred to as Acp5, is secreted by osteoclasts during bone resorption. Release of TRAcP was stimulated by resorbogenic cytokines and repressed by calcitonin (a resorption inhibitor). TRAcP is also known to be expressed in high quantities in active macrophages and dendritic cells and play an essential part in presenting antigens to T cells. Inactive TRAcP released from adipose tissue macrophages has been shown to bring on hyperplastic obesity, keeping lipid metabolism and insulin sensitivity normal. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with human. View All» Application Notes: Western Blot Analysis: A representative lot was used by an independent laboratory in WB. (Janckila, A.J., et al. (1995). Blood. 85:2839-2844.)Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in IP. (Janckila, A.J., et al. (1995). Blood. 85:2839-2844.)Dot Blot Analysis: A representative lot was used by an independent laboratory in DB. (Janckila, A.J., et al. (1995). Blood. 85:2839-2844.)ELISA Analysis: A representative lot was used by an independent laboratory in ELISA. (Janckila, A.J., et al. (1995). Blood. 85:2839-2844.)Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in IC. (Janckila, A.J., et al. (1996). The Journal of Histochemistry and Cytochemistry. 44(3):233-244.) View All» Control: Large malignant B-cells in hairy cell leukemia tissue View All» Quality Assurance: Evaluated by Immunohistochemistry in large malignant B-cells in hairy cell leukemia tissue.Immunohistochemistry Analysis: 1:500 dilution of this antibody detected TRAcP in large malignant B-cells in hairy cell leukemia tissue. View All» Purification Method: Protein G View All» Presentation: Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P13686 View All» Entrez Gene Number: NP_001104504 View All» Gene Symbol: ACP5 View All» Alternate Names:

• Tartrate-resistant acid phosphatase type 5

• TR-AP

• Tartrate-resistant acid ATPase

• TrATPase

• Type 5 acid phosphatase
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunohistochemistry

  • Immunoprecipitation

  • Dot Blot

  • ELISA

  • Immunocytochemistry

  • Western Blotting
    View All» Entrez Gene Summary: This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.CATALYTIC ACTIVITY: A phosphate monoester + H2O = an alcohol + phosphate.COFACTOR: Binds 2 iron ions per subunit.SUBUNIT STRUCTURE: Exists either as monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s). SUBCELLULAR LOCATION: Lysosome. SEQUENCE SIMILARITIES: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family. View All» Product Name: Anti-TRAcP, clone 9C5 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://16ao.com/thread-133051.htm
    © Merck Millipore代理MABF96 Anti-TRAcP Antibody, clone 9C5;抗-TRACP抗体，克隆9C5store at +2℃ to +8℃，产品报价联系微信jinshanbio