货号：MABF35

品牌：Merck Millipore

规格：EA

目录价：￥3108.00

市场价格：￥2641.80

会员价格：￥2486.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CD8a Antibody, clone 3.155 | MABF35 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes CD8a. View All» Molecular Weight: ~27 kDa (calculated MW) View All» Immunogen: Cloned mouse cytolytic T cells. View All» Clone: 3.155 View All» Isotype: IgMκ View All» Background Information: CD8, a member of the immunoglobulin superfamily, is expressed on the majority of thymocytes, a subset of mature T lymphocytes, and NK cells (almost exclusively CD8a homodimers). CD8a acts as a co-receptor with MHC class I-restricted T cell receptors, and through its association with protein tyrosine kinase p56Ick, modulates antigen recognition and T cell activation as well as thymic development. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with mouse. View All» Control: Balb/c mouse thymocytes View All» Quality Assurance: Evaluated by Flow Cytometry in Balb/c mouse thymocytes.Flow Cytometry Analysis: 1 µg of this antibody detected CD8a in Balb/c mouse thymocytes. View All» Purification Method: Ion Exchange Purification View All» Presentation: Purified rat monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P01731 View All» Entrez Gene Number: NP_001074579 View All» Gene Symbol:

• MAL

• p322

• CD8

• CD8a

• Leu2
  View All» Alternate Names:
  • CD8a molecule

  • CD8 antigen, alpha polypeptide (p32)

  • CD8 antigen alpha polypeptide

  • OKT8 T-cell antigen

  • T-lymphocyte differentiation antigen T8/Leu-2

  • Leu2 T-lymphocyte antigen

  • T-cell surface glycoprotein CD8 alpha chain

  • T-cell antigen Leu2

  • T8 T-cell antigen

  • T cell co-receptor

  • CD8a antigen
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Flow Cytometry View All» UniProt Summary: FUNCTION: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.SUBUNIT STRUCTURE: In general heterodimer of an alpha and a beta chain linked by two disulfide bonds. Can also form homodimers.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. SEQUENCE SIMILARITIES: Contains 1 Ig-like V-type (immunoglobulin-like) domain. View All» Product Name: Anti-CD8a, clone 3.155 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Rat View All»
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