货号：MABE64

品牌：Merck Millipore

规格：

目录价：￥3789.00

市场价格：￥3220.65

会员价格：￥3031.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-TDRD7 Antibody, clone E6 | MABE64 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~140 kDa observed View All» Immunogen: Histidine-tagged recombinant protein corresponding to human TDRD7. View All» Clone: E6 View All» Isotype: IgG1κ View All» Background Information: Tudor domain-containing protein 7 (TDRD7) is a ~130 kDa scaffolding protein containing two Tudor domains characteristic to the Tudor domain family of proteins. The exact function of TDRD7 is yet to be defined; however, it has been observed as a component in several regulatory complexes involved in mRNA transport, protein translation apparatus, centrosomal movement and cytoskeleton dynamics. Studies have indicated interaction between TDRD7 and CDK17, PIWIL1 and CABLES1. Expression of TDRD7is primarily observed within the brain and testis, and localized to the mitochondria. View All» Species Reactivity:

• Human

• Rat
  View All» Species Reactivity Note: Demonstrated to react with human. Predicted to react with rat based on 100% sequence homology and cited to react with rat (Skorkhod, O. et al. (2008). View All» Application Notes: Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in IP (rat bran lysate) (Skorkhod, O. et al. (2008).Immunocytochemistry Analysis: A representative lot was used by an independent laboratory to detect TDRD7 in HEK293 cells by IC (Skorkhod, O. et al. (2008). View All» Control: Human testis tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human testis tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected TDRD7 in 10 µg of human testis tissue lysate. View All» Purification Method: Protein G Purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8NHU6 View All» Entrez Gene Number: NP_055105 View All» Gene Symbol:
  • TDRD7

  • PCTAIRE2BP

  • Trap

  • TRAP
    View All» Alternate Names:
    • tudor domain containing 7

    • tudor domain-containing protein 7

    • Tudor repeat associator with PCTAIRE

    • PCTAIRE2-binding protein
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunoprecipitation

      • Immunocytochemistry
        View All» UniProt Summary: SUBUNIT STRUCTURE: Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. Found in a complex containing CABLES1, CDK16 and CDK17. Interacts with CABLES1, CDK17 and PIWIL1 (By similarity).SUBCELLULAR LOCATION: Cytoplasm (By similarity). Note: Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By similarity).SEQUENCE SIMILARITIES: Contains 2 Tudor domains. View All» Product Name: Anti-TDRD7, clone E6 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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