货号：MABE116

品牌：Merck Millipore

规格：

目录价：￥4110.00

市场价格：￥3493.50

会员价格：￥3288.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-SRp20 Antibody, clone 7B4 | MABE116 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~19 kDa observed View All» Epitope: 0 View All» Immunogen: KLH-conjugated linear peptide corresponding to human SRp20. View All» Clone: 7B4 View All» Isotype: IgG1κ View All» Background Information: Splicing factor, arginine/serine-rich 3 (SRp20) is a member of the splicing factor SR family and contains an RRP (RNA recognition motif) domain. SRp20 has been shown as being localized to nuclear sites of RNA transcription and localization of SR protein. It is involved in mediating RNA export in association with the proliferation and/or maturation of cells. SRp20 has also been implicated in recent studies as having a regulatory role in the early-to-late switch of Papillomavirus, and as being target for the regulation of splicing modifications by the β-catenin/TCF4 pathway. Up-regulation of SRp20 has also been linked with malignant epithelial ovarian cancer. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with human. Predicted to react with mouse and rat based on 100% sequence homology. View All» Application Notes: Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in IC (Neugebauer, K.M. , et al., 1997). View All» Control: HeLa nuclear extract View All» Quality Assurance: Evaluated by Western Blot in HeLa nuclear extract.Western Blot Analysis: 0.5 µg/mL of this antibody detected SRp20 in 10 µg of HeLa nuclear extract. View All» Purification Method: Protein G Purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P84103 View All» Entrez Gene Number: NP_003008 View All» Gene Symbol:
  • SRp20

  • SFRS3
    View All» Alternate Names:
    • splicing factor, arginine/serine-rich 3

    • Pre-mRNA-splicing factor SRP20

    • splicing factor, arginine/serine-rich, 20-kD
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry
        View All» UniProt Summary: FUNCTION: May be involved in RNA processing in relation with cellular proliferation and/or maturation.SUBUNIT STRUCTURE: Interacts with CPSF6, RBMY1A1 and SFRS12. SUBCELLULAR LOCATION: Nucleus. PTM: Extensively phosphorylated on serine residues in the RS domain (By similarity). SEQUENCE SIMILARITIES: Belongs to the splicing factor SR family.Contains 1 RRM (RNA recognition motif) domain. View All» Product Name: Anti-SRp20, clone 7B4 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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