货号:MABD86
品牌:Merck Millipore
规格:100Ug
目录价:¥5207.00
市场价格:¥4425.95
会员价格:¥4165.60
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Description:
Anti-CD349/Frizzled 9 Antibody, clone W3C4 | MABD86
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Molecular Weight:
65 kDa calculated
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Immunogen:
Whole WERI-RB-1 cells
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Clone:
W3C4-hMSC marker
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Isotype:
IgMκ
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Background Information:
CD349 is a member of the Frizzled family, known as Frizzled-9 (Fz9, FZD9, hFz9, or FzE6) which was originally described as FZD3. Ten frizzled member have been identified in humans. FZD9 is a seven transmembrane G-protein-coupled receptor (GPCR), a receptor for Wnt proteins. It is involved in the activation of Wnt/β-catenin pathway (canonic Wnt signaling). FZD9 is predominately expressed in fetal and adult brain, testis, eye, skeletal muscle and kidney and is also expressed on Mesenchymal stem cells, and neural precursor cells. Frizzled proteins play important roles in controlling cell fate, proliferation, migration, tissue architecture and organogenesis during embryonic development and in adult organisms. FZD9 is an important factor for nervous system development and is critical for hippocampal development.
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Species Reactivity:
Human
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Species Reactivity Note:
Demonstrated to react with Human.
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Control:
WERI-RB-1 cells
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Quality Assurance:
Evaluated by Flow Cytometry on WERI-RB-1 cells Flow Cytometry Analysis: 4 µg/mL of this antibody detected CD349/Frizzled 9 on 1X10^5 WERI-RB-1 cells.
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Purification Method:
Purified by ion-exchange chromatography
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Presentation:
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
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Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
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UniProt Number:
O00144
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Entrez Gene Number:
NP_003499
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Gene Symbol:
-
FZD9
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FZD3
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Alternate Names:
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CD349
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Frizzled-9
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Frizzled 9
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FZ-9
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FzE6
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FzD3
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Flow Cytometry
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Product Name:
Anti-CD349/Frizzled 9, clone W3C4
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Concentration:
0.5 mg/mL
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Antibody Type:
Monoclonal Antibody
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Qty/Pk:
100 μg
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Format:
Purified
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Host:
Mouse
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