货号：MABC42

品牌：Merck Millipore

规格：50Ug

目录价：￥5666.00

市场价格：￥4816.10

会员价格：￥4532.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Pleiotrophin Antibody, clone 3B10 | MABC42 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~20 kDa observed View All» Immunogen: Recombinant protein corresponding to chicken Pleiotrophin. View All» Clone: 3B10 View All» Isotype: IgG1κ View All» Background Information: Pleiotrophin (PTN) also called Neurite Growth-promoting Factor 1 (NEGF1) or HARP (Heparin affin regulatory peptide) is a new member of the heparin-binding neurotrophic factor family. PTN plays an important role in development processess and promotion of neurite extension. During embryonic development, pleiotrophin is expressed in the central and peripheral nervous system, lung, kidney, gut and bone. Pleiotrophin is also expressed by several tumor cells and is thought to be involved in tumor angiogenesis. PTN initiates an angiogenic switch in different cancer models and acts as an angiogenic factor. PTN does this through an interaction with endothelial cells to initiate proliferation, migration, and tube formation. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with human. View All» Application Notes: Immunohistochemistry Analysis: A 1:500 dilution from a previous lot detected Pleiotrophin in papillary squamous cell carcinoma tissue. View All» Control: Human placenta tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human placenta tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected Pleiotrophin in 10 µg of human placenta tissue lysate. View All» Purification Method: Protein G Purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing PBS without 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P32760 View All» Entrez Gene Number: XP_416358 View All» Gene Symbol:

• OSF-1

• PTN

• NEGF1

• HBNF-1

• HBBM

• HBGF8

• HBGF-8

• HBNF1

• HB-GAM

• HARP

• HBNF1
  View All» Alternate Names:
  • pleiotrophin

  • neurite growth-promoting factor 1

  • Heparin-binding brain mitogen

  • heparin binding growth factor 8

  • Heparin-binding growth-associated molecule

  • heparin affin regulatory protein

  • Heparin-binding neurite outgrowth-promoting factor 1

  • pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)

  • Osteoblast-specific factor 1

  • Heparin-binding growth factor 8
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Western Blotting
      View All» UniProt Summary: FUNCTION: Heparin binding mitogenic protein. Has neurite extension activity.SUBCELLULAR LOCATION: Secreted. SEQUENCE SIMILARITIES: Belongs to the pleiotrophin family. View All» Product Name: Anti-Pleiotrophin, clone 3B10 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 50 μg View All» Format: Purified View All» Host: Mouse View All»
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      © Merck Millipore代理MABC42 Anti-Pleiotrophin Antibody, clone 3B10;store at -20℃，产品报价联系微信jinshanbio