货号：MABC196

品牌：Merck Millipore

规格：100Ug

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY | MABC196 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~42 kDa observed View All» Immunogen: Recombinant protein corresponding to human Chitinase-3-like protein 1 (YKL-40). View All» Clone: mAY View All» Isotype: IgG1κ View All» Background Information: YKL-40 (Chitinase-3-like protein 1; human cartilage glycoprotein 39) is a secreted glycoprotein belonging to the glycosyl hydrolase 18 (GH18) family. It is found primarily in chondrocytes, activated macrophages, and hepatocytes. The precise biological function of YKL-40 is still unknown; however, recent studies suggest that YKL-40 may play a role in cell differentiation and inflammation. YKL-40 is elevated in the sera of patients with inflammatory diseases or cancer, and it is currently being investigated as a potential biomarker for these conditions. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Chitinase-3-like protein 1 (YKL-40) in U87 cells (This protein blocks tumor angiogenesis tube formation and progression (Faibish, M., et al. (2011). Mol Cancer Ther. 10(5):742-751.)).Activity Assay Analysis: A representative lot from an independent laboratory neutralized Chitinase-3-like protein 1 in a neutralization assay (Faibish, M., et al. (2011). Mol Cancer Ther. 10(5):742-751.). View All» Control: MG-63 conditioned media View All» Quality Assurance: Evaluated by Western Blot in MG-63 conditioned media.Western Blot Analysis: 0.5 µg/mL of this antibody detected Chitinase-3-like protein 1 (YKL-40) in 10 µg of MG-63 conditioned media (This protein blocks tumor angiogenesis tube formation and progression (Faibish, M., et al. (2011). Mol Cancer Ther. 10(5):742-751.)). View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing PBS without preservatives. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P36222 View All» Entrez Gene Number: NP_001267 View All» Gene Symbol: CHI3L1 View All» Alternate Names:

• Chitinase-3-like protein 1

• 39 kDa synovial protein

• Cartilage glycoprotein 39

• CGP-39

• GP-39

• hCGP-39

• YKL-40
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunohistochemistry

  • Activity Assay
    View All» Product Name: Anti-Chitinase-3-like protein 1 (YKL-40), clone mAY View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Target / Localization: Both normal and osteoarthritic chondrocytes View All» Format: Purified View All» Host: Mouse View All»
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    © Merck Millipore代理MABC196 Anti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY;抗-几丁质酶-3样蛋白1（YKL-40）抗体，克隆mAYstore at -2，产品报价联系微信jinshanbio