货号：05-1540

品牌：Merck Millipore

规格：100Ug

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Gemin2 Antibody, clone 2E17 | 05-1540 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Antibody recognizes Gemin-2. View All» Molecular Weight: 32 kDa Calculated View All» Epitope: N/A View All» Immunogen: His-tagged recombinant protein corresponding to human Gemin-2. View All» Clone: 2E17 View All» Isotype: IgG1κ View All» Background Information: Gemin-2 (also known as SIP1 or SMN interacting protein1) is a part of the SMN complex. The SMN complex plays a role in RNA metabolism and in splicing regulation. As part of the SMN complex Gemin-2 interacts directly with Gemin-5 in a heteromeric complex that includes Gemin-3, Gemin-4, Gemin-6. This macromolecular complex (SMN complex) mediates assembly of spliceosomal snRNA complexes containing U1 and U5. View All» Species Reactivity:

• Human

• Mouse
  View All» Species Reactivity Note: Reacts with Human. Predicted to recognize mouse based on 100% sequence homology. View All» Application Notes: Immunocytochemistry:Cited in Battle, D.J., et. al (2007). J. Biol. Chem. 282: 27953 - 27959 and Zhang, Z., et. al (2008). Cell, 133:85-600. using a representative lot.ELISA: Cited in Zhang, Z., et. al (2008). Cell, 133:85-600. Immunoprecipitation:Cited in Battle, D.J., et. al(2007). J. Biol. Chem. 282: 27953 - 27959 using a representative lot. View All» Control: HeLa cell lysates. View All» Quality Assurance: Evaluated by Western Blotting in HeLa cell lysates.Western Blotting Analysis: 0.5 µg/mL of this antibody detected Gemin-2 in HeLa cell lysates. View All» Purification Method: Protein G purfied View All» Presentation: Purified mouse IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: O14893 View All» Entrez Gene Number: NM_001009182.1 View All» Gene Symbol:
  • SIP1

  • SIP1-delta
    View All» Alternate Names:
    • GEMIN2

    • Gemin2

    • Component of gems

    • SMN interacting protein 1-delta

    • SMN-interacting protein 1

    • survival interacting protein 1

    • survival of motor neuron protein interacting protein
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry

      • ELISA

      • Immunoprecipitation
        View All» UniProt Summary: Function The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.Subunit structure Part of the core SMN complex that contains SMN1, SIP1/GEMIN2, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP. Interacts directly with GEMIN5. View All» Product Name: Anti-Gemin2, clone 2E17 Antibody (05-1540) View All» Concentration: 1.0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
        © 金山科研平台是专业的授权总代理区域代理经销平台。
        © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
        © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
        © 本文地址：https://16ao.com/thread-132634.htm
        © Merck Millipore代理05-1540 Anti-Gemin2 Antibody, clone 2E17;store at +2℃ to +8℃，产品报价联系微信jinshanbio