货号：05-1004

品牌：Merck Millipore

规格：

目录价：￥3639.00

市场价格：￥3093.15

会员价格：￥2911.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho-EGFR (Tyr1173) Antibody, clone 3G3.2 | 05-1004 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes phosphorylated EGFR (Tyr1173). View All» Molecular Weight: 175 kDa View All» Epitope: Phosphorylated Tyr1173 View All» Immunogen: KLH-conjugated linear peptide corresponding to residues surrounding Tyr1173 of EGFR. View All» Modifications: Phosphorylation View All» Clone: 3G3.2 View All» Isotype: IgG1κ View All» Background Information: The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. EGFR (epidermal growth factor receptor) exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor α (TGFα). EGFR dimerization stimulates its intrinsic intracellular protein-tyrosine kinase activity. As a result, autophosphorylation of five tyrosine (Y) residues in the C-terminal domain of EGFR occurs. View All» Species Reactivity: Human View All» Species Reactivity Note: Proven to react with human. View All» Application Notes: Flow Cytometry Analysis: A431 cells stained using 10 ug/mL of anti-phospho -EGFR (Tyr1173).Immunocytochemistry Analysis: A 1:500 dilution of this antibody detected anti-phospho-EGFR (Tyr1173) in EGF treated A431 lysates.Immunohistochemistry Analysis: A 1:100 dilution of this detected anti-phospho-EGFR (Tyr1173) in serous ovarian cancer. View All» Control: EGF treated A431 cell lysate View All» Quality Assurance: Evaluated by Western Blot in EGF treated and untreated A431 cell lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected phospho-EGFR (Tyr1173) on 15 µg of EGF treated A431 cell lysate. View All» Purification Method: Protein G purfied View All» Presentation: Purified rabbit ascites containing 0.1 M Tris-glycine, pH 7.4, 150 mM NaCl and 0.05% sodium azide. View All» Storage Conditions: Maintain refrigerated at 2-8°C for 1 year from date of receipt. View All» UniProt Number: Q86T13 View All» Entrez Gene Number: NP_005219.2 View All» Gene Symbol:

• C14orf27

• CEG1

• EGFR-5

• EGFR5

• OTTHUMP00000178873
  View All» Alternate Names:
  • C-type lectin domain family 14, member A

  • ClECT and EGF-like domain containing protein

  • Epidermal growth factor receptor 5

  • chromosome 14 open reading frame 27
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Flow Cytometry

    • Immunohistochemistry

    • Immunocytochemistry
      View All» Entrez Gene Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. View All» UniProt Summary: SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein Potential. SEQUENCE SIMILARITIES: Contains 1 C-type lectin domain.Contains 1 EGF-like domain. View All» Product Name: Anti-phospho-EGFR (Tyr1173), clone 3G3.2 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://16ao.com/thread-132329.htm
      © Merck Millipore代理05-1004 Anti-phospho-EGFR (Tyr1173), clone 3G3.2 (mouse monoclonal)，产品报价联系微信jinshanbio