货号：MAB5534

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Synaptojanin 1 Antibody, clone AC1 | MAB5534 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Synaptojanin 1 View All» Immunogen: Fusion protein from rat Synaptojanin-145. View All» Clone: AC1 View All» Isotype: IgG1 View All» Species Reactivity: Rat View All» Application Notes: Western blot Immunogold labeling of homogenized rat retinas or lysed brain synaptosomes. Optimal working dilutions must be determined by end user. View All» Presentation: Ascites fluid. Liquid. Contains no preservative. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: O43426 View All» Entrez Gene Number:

• NM_003895.2

• NM_203446.1
  View All» Gene Symbol:
  • SYNJ1

  • KIAA0910

  • INPP5G

  • Synaptojanin-1

  • EC 3.1.3.36
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Synaptojanin-1 is a phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2) that has a role in clathrin-coated pit dynamics Perera et al. (2006) [PubMed 17158794].[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: O43426 # Inositol 5-phosphatase which has a role in clathrin- mediated endocytosis.SIZE: 1575 amino acids; 173346 Da SUBUNIT: Binds AMPH, SH3GL1, SH3GL2 and SH3GL3.SUBCELLULAR LOCATION: Cytoplasm (By similarity).TISSUE SPECIFICITY: Concentrated at clathrin-coated endocytic intermediates in nerve terminals. Isoform 1 is more enriched than isoform 2 in developing brain as well as non-neuronal cells. Isoform 2 is very abundant in nerve terminals.DOMAIN: SwissProt: O43426 Binds to EPS15 (a clathrin coat-associated protein) via a C-terminal domain containing three Asn-Pro-Phe (NPF) repeats (By similarity). & The C-terminal proline-rich region mediates binding to a variety of SH3 domain-containing proteins including AMPH, SH3GL1, SH3GL2, SH3GL3 and GRB2.SIMILARITY: Belongs to the synaptojanin family. & In the central section; belongs to the inositol-1,4,5- trisphosphate 5-phosphatase family. & Contains 1 RRM (RNA recognition motif) domain. & Contains 1 SAC domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Synaptojanin 1 Antibody, clone AC1 | MAB5534 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Target / Localization: Presynaptic View All» Format: Ascites View All» Host: Mouse View All»
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