货号：MAB5504A4

品牌：Merck Millipore

规格：100UL

目录价：￥6588.00

市场价格：￥5599.80

会员价格：￥5270.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Vesicular Glutamate Transporter 2 Antibody, Alexa Fluor® 488 | MAB5504A4 View All» Promotional Text: Special Offer on Antibodies! Click Here! View All» Molecular Weight: The unconjugated parent antibody (Cat. No. MAB5504) has an observed molecular weight at ~56 kDa. View All» Immunogen: Recombinant protein from rat VGLUT2. View All» Clone: 8G9.2 View All» Isotype: IgG1 View All» Background Information: Vesicular Glutamate Transporter 2 (VGLUT2) is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity. View All» Species Reactivity:

• Mouse

• Rat

• Human
  View All» Species Reactivity Note: Demonstrated to react with Mouse and Rat. Predicted to react with Human based on 100% sequence homology. View All» Control: Adult mouse brain tissue View All» Quality Assurance: Evaluated by Immunohistochemistry in adult mouse brain tissue.Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Vesicular Glutamate Transporter 2 in adult mouse brain tissue. View All» Purification Method: Protein A purified View All» Presentation: Purified mouse monoclonal IgG1 conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA. View All» Storage Conditions: Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt. View All» UniProt Number: Q9JI12 View All» Entrez Gene Number: NP_445879 View All» Gene Symbol:
  • Slc17a6

  • Dnpi

  • Vglut2

  • VGLUT2
    View All» Alternate Names:
    • Vesicular glutamate transporter 2

    • VGluT2

    • Differentiation-associated BNPI

    • Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter

    • Solute carrier family 17 member 6
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry View All» Entrez Gene Summary: Na+-dependent inorganic phosphate cotransporter; involved in Ca2+-dependent glutamate release from astrocytes [RGD]. View All» UniProt Summary: FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. May also mediate the transport of inorganic phosphate. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein (Potential). Cell junction, synapse, synaptosome. TISSUE SPECIFICITY: Expressed in brain (at protein level). Expressed in brainstem, deep nuclei, septal nuclei, nuclei of the diagonal band, frontal cortex, hypothalamus, midbrain, parietal cortex and temporal cortex. Also expressed in pineal gland and islets of Langerhans. SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. SIZE: 582 amino acids; 64392 Da View All» Product Name: Anti-Vesicular Glutamate Transporter 2, Alexa Fluor® 488 Conj. View All» Qty/Pk: 100 µL View All» Format: AlexaFluor®488 View All» Host: Mouse View All»
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