货号：MAB5504

品牌：Merck Millipore

规格：100Ug

目录价：￥6127.00

市场价格：￥5207.95

会员价格：￥4901.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Vesicular Glutamate Transporter 2 Antibody | MAB5504 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with VGLUT2 (Vesicular Glutamate Transporter 2). View All» Molecular Weight: 56 kDa View All» Immunogen: Recombinant protein from rat VGLUT2. View All» Clone: 8G9.2 View All» Isotype: IgG1 View All» Background Information: Vesicular Glutamate Transporter 2 (VGLUT2) is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Mouse and rat. Expected to react with human based on sequence homology. View All» Application Notes: Immunohistochemistry: A 1:50-1:300 dilution of a previous lot worked using ABC with NiDAB on floating mouse brain sections.Optimal working dilutions must be determined by end user. View All» Control: Brain tissue View All» Quality Assurance: Evaluated by Western Blot on Mouse brain lysates.Western Blotting Analysis: 1:500 dilution of this antibody detected VGLUT2 on 10 µg of Mouse brain lysates. View All» Purification Method: Protein A purfied View All» Presentation: Mouse monoclonal in PBS containing 0.1% sodium azide. View All» Storage Conditions: Stable for 1 year at from date of receipt. View All» UniProt Number: Q9JI12 View All» Entrez Gene Number: NM_020346.1 View All» Gene Symbol:
  • SLC17A6

  • DNPI

  • VGLUT2
    View All» Alternate Names: VGLUT2 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry
      View All» UniProt Summary: FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. May also mediate the transport of inorganic phosphate. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein (Potential). Cell junction, synapse, synaptosome. TISSUE SPECIFICITY: Expressed in brain (at protein level). Expressed in brainstem, deep nuclei, septal nuclei, nuclei of the diagonal band, frontal cortex, hypothalamus, midbrain, parietal cortex and temporal cortex. Also expressed in pineal gland and islets of Langerhans. SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. SIZE: 582 amino acids; 64392 Da View All» Brand Family: Chemicon View All» Product Name: Anti-Vesicular Glutamate Transporter 2 Antibody | MAB5504 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Target / Localization: Presynaptic View All» Format: Purified View All» Host: Mouse View All»
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