货号：MAB5460

品牌：Merck Millipore

规格：100Ul

目录价：￥6434.00

市场价格：￥5468.90

会员价格：￥5147.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Nkx2.1 Antibody | MAB5460 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Nkx2.1 (Thyroid Transcription Factor-1, TTF-1). View All» Immunogen: Recombinant rat Nkx2.1. View All» Isotype: IgG1 View All» Species Reactivity: Human View All» Application Notes: Western blot. The antibody reacts with a 40 kDa band in immunoblots of nuclear extracts or whole cell lysates from the Nkx2.1 positive cell lines MLE15, H441-4, H345 and rat type II pmeumocyte cells. Immunohistochemistry. The antibody can be used on formalin-fixed paraffin embedded tissue. Heat induced epitope retrieval is recommended. Optimal working dilutions must be determined by end user. View All» Presentation: Ascites fluid. Liquid. Contains no preservative. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P43699 View All» Entrez Gene Number:

• NM_001079668.1

• NM_003317.3
  View All» Gene Symbol:
  • NKX2-1

  • BCH

  • TEBP

  • TITF1

  • TTF1

  • NKX2.1

  • NK-2

  • TTF-1

  • BHC

  • NKX2A
    View All» Alternate Names: TTF-1; Thyroid Transcription Factor-1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry (Paraffin)
      View All» UniProt Summary: FUNCTION: SwissProt: P43699 # Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis.SIZE: 371 amino acids; 38596 Da SUBCELLULAR LOCATION: Nucleus.TISSUE SPECIFICITY: Thyroid and lung.PTM: Phosphorylated on serine residues (By similarity).DISEASE: SwissProt: P43699 # Defects in TITF1 are the cause of benign hereditary chorea (BHC) [MIM:118700]; also known as hereditary chorea without dementia. BHC is an autosomal dominant movement disorder. The early onset of symptoms (usully before the age of 5) and the observation that in some BHC families the symptoms tend to decrease in adulthood suggests that the disorder results from a developmental disturbance of the brain. BHC is non-progressive and patients have normal or slightly below normal intelligence. There is considerable inter- and intrafamilial variability, including dysarthria, axial distonia and gait disturbances. & Defects in TITF1 are the cause of choreoathetosis, hypothyroidism, and neonatal respiratory distress (CHNRD) [MIM:610978]. This syndrome include neurological, thyroid, and respiratory problems.SIMILARITY: SwissProt: P43699 ## Belongs to the NK-2 homeobox family. & Contains 1 homeobox DNA-binding domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Nkx2.1 Antibody | MAB5460 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
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      © Merck Millipore代理MAB5460 Anti-Nkx2.1 Antibody, clone 8G7-G3-1;抗Nkx2.1抗体，克隆8G7-G3-1store at -20℃，产品报价联系微信jinshanbio