货号：MAB5434

品牌：Merck Millipore

规格：

目录价：￥3639.00

市场价格：￥3093.15

会员价格：￥2911.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Oct-1 Antibody, clone YL15 | MAB5434 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with Oct-1. Recognizes a ~96kDa protein in nuclear extracts of HeLa cells. View All» Immunogen: Full length recombinant human Oct-1 protein. View All» Clone: YL15 View All» Isotype: IgG1 View All» Background Information: Oct proteins belong to the POU domain transcription factor family (for review see, Herr et al. (1995) Genes and Dev. 9:1679-1693). POU domain is a bipartite module containing POU homeo and POU specific subdomains, identified in more than 30 nuclear proteins that recognize relative cis-elements in promoters, enhancers and silencers of many genes. Oct-1 and Oct-2 proteins recognize the octamer consensus sequence ATGCAAAT and with lower affinity for oct-related sequences. View All» Species Reactivity:

• Human

• Mouse
  View All» Application Notes: Western blot: 2.5 μg/mL. Recognizes the ~96 kDa protein. Immunocytochemistry: 1-2μg/mL Immunoprecipitation: 2-5 μg/mL Optimal working dilutions must be determined by end user. View All» Presentation: Purified immunoglobulin. Liquid in PBS containing 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. View All» UniProt Number: P14859 View All» Entrez Gene Number: NM_002697.2 View All» Gene Symbol:
  • POU2F1

  • OCT1

  • NF-A1

  • OTF1

  • OTF-1

  • Oct-1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting

    • Immunocytochemistry
      View All» UniProt Summary: FUNCTION: SwissProt: P14859 # Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity).SIZE: 743 amino acids; 76472 Da SUBUNIT: Interacts with NR3C1, AR, PGR and HCFC1.SUBCELLULAR LOCATION: Nucleus.TISSUE SPECIFICITY: Ubiquitous. Isoform 2 is lymphocyte-specific.PTM: Phosphorylated by PRKDC.SIMILARITY: SwissProt: P14859 ## Belongs to the POU transcription factor family. Class- 2 subfamily. & Contains 1 homeobox DNA-binding domain. & Contains 1 POU-specific domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Oct-1 Antibody, clone YL15 | MAB5434 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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