货号：MAB5358

品牌：Merck Millipore

规格：

目录价：￥3990.00

市场价格：￥3391.50

会员价格：￥3192.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CDCREL-1 Antibody, clone SP18 | MAB5358 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: CDCrel-1. Specific for CDCrel-1 and does not cross react with CDCrel-2 fusion protein. View All» Immunogen: Immunoprecipitate of human brain. View All» Clone: SP18 View All» Isotype: IgG1 View All» Species Reactivity:

• Human

• Rat
  View All» Application Notes: Western blot. 1:100 using an HRP conjugated secondary antibody with 4CN as the substrate. Recognizes a protein of 40 kDa in rat brain and 40 kDa and 38 kDa in human brain. Suggested blocking buffer is 5% carnation non fat milk in TBS. Immunohistochemistry on formalin fixed (24 hours to 2 weeks), paraffin embedded tissue sections. Suggested blocking buffer is 5% carnation non fat milk in TBS. Permeablize with Triton X-100. ELISA, direct Optimal working dilutions must be determined by the end user. View All» Presentation: Purified immunoglobulin. Liquid in 0.02M Phosphate buffer with 0.25M NaCl and 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8C in undiluted aliquots up to 6 months after date of receipt. View All» UniProt Number: Q99719 View All» Entrez Gene Number: NM_002688.4 View All» Gene Symbol:
  • SEPT5

  • Septin-5

  • PNUTL1

  • CDCREL1

  • CDCREL

  • H5

  • HCDCREL-1

  • CDCrel-1

  • CDCREL-1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Western Blotting

    • Immunohistochemistry (Paraffin)
      View All» Entrez Gene Summary: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Two transcripts of this gene, a major one of 2.2 kb and a minor one of 3.5 kb, have been observed. The 2.2 kb form results from the utilization of a non-consensus polyA signal (AACAAT). In the absence of polyadenylation from this imperfect site, the consensus polyA signal of the downstream neighboring gene (GP1BB; platelet glycoprotein Ib) is used, resulting in the 3.5 kb transcript. An alternatively spliced transcript variant with a different 5' end has also been identified, but its full-length nature has not been completely determined. View All» UniProt Summary: FUNCTION: SwissProt: Q99719 # Involved in cytokinesis (Potential).SIZE: 369 amino acids; 42777 Da SUBUNIT: May assemble into a multicomponent structure.SIMILARITY: SwissProt: Q99719 ## Belongs to the septin family. View All» Brand Family: Chemicon View All» Product Name: Anti-CDCREL-1 Antibody, clone SP18 | MAB5358 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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