货号：04-460

品牌：Merck Millipore

规格：

目录价：￥3475.00

市场价格：￥2953.75

会员价格：￥2780.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CD3 ε Antibody, Rabbit | 04-460 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes a region composed of residues encompassing the cytoplasmic domain of human CD3. This antibody does not recognize the other subunits of CD3. View All» Molecular Weight: 23kDa View All» Immunogen: KLH-conjugated synthetic peptide composed of residues encompassing the cytoplasmic domain of human CD3. View All» Isotype: IgG View All» Species Reactivity: Human View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Presentation: 100 μL of rabbit monoclonal IgG in 60% storage buffer (50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 0.01% sodium azide and 0.05% BSA) and 40% glycerol. View All» Storage Conditions: 2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage. View All» UniProt Number: P07766 View All» Entrez Gene Number: NM_000733.2 View All» Gene Symbol:

• CD3E

• T3E

• TCRE
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunofluorescence

  • Western Blotting
    View All» Entrez Gene Summary: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. View All» UniProt Summary: FUNCTION: SwissProt: P07766 # The CD3 complex mediates signal transduction.SIZE: 207 amino acids; 23147 Da SUBUNIT: The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.SIMILARITY: SwissProt: P07766 ## Contains 1 Ig-like (immunoglobulin-like) domain. & Contains 1 ITAM domain. View All» Brand Family: Upstate View All» Product Name: Anti-CD3 ε Antibody, Rabbit | 04-460 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rabbit View All»
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