货号：04-382

品牌：Merck Millipore

规格：

目录价：￥3510.00

市场价格：￥2983.50

会员价格：￥2808.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MKK4 CT Antibody | 04-382 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes MKK4. View All» Molecular Weight: 44 kDa View All» Epitope: C-terminus View All» Immunogen: KLH-conjugated synthetic peptide corresponding to residues in the C-term of human MKK4. View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Western Blot: 1:1000. Immunoprecipitation: 1:50. The use of protein G agarose is recommended. Flow Cytometry: 1:50. Immunohistochemistry: 1:50-1:100 on paraffin-embeddedsections of human lung adenocarcinoma. Optimal working dilutions must be determined by the end user. View All» Quality Assurance: Routinely evaluated by immunoblot analysis. View All» Purification Method: Protein G purfied View All» Presentation: Rabbit monoclonal IgG in 30 mM Tris-Glycine (pH 7.4), 90 mM NaCl, 0.006% sodium azide, 0.03% BSA and 40% glycerol. View All» Storage Conditions: 2 years at -20°C from date of shipment. View All» UniProt Number: P45985 View All» Entrez Gene Number: NM_003010.2 View All» Gene Symbol:
  • MAP2K4

  • SERK1

  • MAPKK4

  • JNKK1

  • SEK1

  • PRKMK4

  • MEK4

  • MKK4

  • JNKK
    View All» Alternate Names: JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SEK1, SERK1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Flow Cytometry

    • Immunohistochemistry (Paraffin)

    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. View All» UniProt Summary: FUNCTION: SwissProt: P45985 # Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).SIZE: 399 amino acids; 44288 Da SUBUNIT: Interacts with SPAG9 (By similarity).TISSUE SPECIFICITY: Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.PTM: Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases (By similarity).SIMILARITY: SwissProt: P45985 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. & Contains 1 protein kinase domain. View All» Brand Family: Upstate View All» Product Name: Anti-MKK4 CT Antibody | 04-382 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rabbit View All»
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