货号：04-368

品牌：Merck Millipore

规格：

目录价：￥3346.00

市场价格：￥2844.10

会员价格：￥2676.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-IRAK-4 (N-term) Antibody, clone Y279, Rabbit Monoclonal | 04-368 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the N-terminus of IRAK-4. View All» Molecular Weight: ~52 kDa observed View All» Epitope: N-terminus View All» Immunogen: Synthetic peptide corresponding to the N-terminus of human IRAK-4. View All» Clone: Y279 View All» Isotype: IgG View All» Background Information: IRAK-4 is a member of the interleukin-1 receptor-associated kinase (IRAK) family. The IRAK family is implicated in the Toll-like receptor (TLR) and Il-1R signaling pathway (1). Upon phosphorylation, IRAK-4 interacts with IRAK-1, MYD88 and TRAF6 to form a complex, and activate NF-kB and MAPK pathways (2-3). IRAK-4 phosphorylates and activates IRAK-1 at thr387 and is also known to interact with IRAK-1 but not with the other IRAK members. Additionally, like IRAK-1, IRAK-4 possesses an auto and crossphosphorylation kinase activity (4). View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Immunocytochemistry Analysis: A 1:50-100 dilution from a representative lot was used in IC. View All» Control: Daudi cell lysate View All» Quality Assurance: Evaluated by Western Blot in Jurkat cell lysateWesternBlot Analysis: A 1:1,000 to 1:10,000 dilution of this antibody detected IRAK-4 in Jurkat cell lysate. View All» Purification Method: Unpurified View All» Presentation: Rabbit Monoclonal in buffer containing glycerol, BSA, and sodium azide. View All» Storage Conditions: Stable for 1 year at -20ºC from date of receipt.Handling Recommendations: Upon first thaw, and prior to removing cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20ºC. Avoid freeze/thaw cycles, which may damage IgG and affect product performance.Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: Q9NWZ3 View All» Entrez Gene Number: Q9NWZ3 View All» Gene Symbol:

• NY-REN-64

• IRAK-4

• EC 2.7.11.1

• IPD1

• REN64

• EC 2.7.11
  View All» Alternate Names:
  • interleukin-1 receptor-associated kinase 4

  • Renal carcinoma antigen NY-REN-64
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunocytochemistry
      View All» Product Name: Anti-IRAK-4 (N-term), clone Y279, Rabbit Monoclonal View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Unpurified View All» Host: Rabbit View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://16ao.com/thread-131752.htm
      © Merck Millipore代理04-368 Anti-IRAK-4 (N-term), clone Y279, Rabbit Monoclonal，产品报价联系微信jinshanbio